(R)-AM1241

(R)-AM1241 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

(R)-AM1241 binds to cannabinoid (CB) receptors and has greater than 100-fold selectivity for the CB₂ over the CB₁ receptor (K_is = 15 and 5,000 nM, respectively, in a membrane assay using human receptors). (R)-AM1241 acts as an agonist at human CB₂ receptors (EC₅₀ = 118 nM) but an inverse agonist at rat and mouse CB₂ receptors (EC₅₀s = 315 and 341 nM, respectively). Similar to the racemate AM1241 , (R)-AM1241 produces antinociception to thermal, but not mechanical, pain in rats. The pain-reducing effect of (R)-AM1241 is blocked by the CB₂-specific inhibitor SR 144528 but not by either the CB₁-selective inhibitor rimonabant or the opioid receptor blocker naloxone ( | ISO60191).

(R)-AM1241 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(R)-AM1241 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58

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• (R)-AM1241
• ZUHIXXCLLBMBDW-MRXNPFEDSA-N
• (R)-AM1241 Exclusive
• (R) AM1241,(R)-AM-1241,(R)AM1241
• Methanone, (2-iodo-5-nitrophenyl)[1-[[(2R)-1-methyl-2-piperidinyl]methyl]-1H-indol-3-yl]-
• 444912-51-0