Hydroxypioglitazone

146062-44-4

CAS-Nr.: 146062-44-4

Englisch Name:: Hydroxypioglitazone

Synonyma:: Leriglitazone;HYDROXYPIOGLITAZONE;Hydroxypioglitazone M4;Pioglitazone Impurity 4;Pioglitazone Impurity 18;Pioglitazone M4 Metabolite;Pioglitazone, hydroxy M-IV;Hydroxy Pioglitazone (M-IV);Hydroxy Pioglitazone Solution, 100ppm;5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY] PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE

CBNumber:: CB1299313

Summenformel:: C19H20N2O4S

Molgewicht:: 372.44

MOL-Datei:: 146062-44-4.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 85

Hydroxypioglitazone Eigenschaften

Schmelzpunkt:: 157-1580C

Siedepunkt:: 627.6±55.0 °C(Predicted)

Dichte: 1.325±0.06 g/cm3(Predicted)

storage temp.: -20°C Freezer, Under Inert Atmosphere

Löslichkeit: DMSO (Slightly), Methanol (Slightly, Sonicated)

pka: 6.35±0.50(Predicted)

Aggregatzustand: Solid

Farbe: White to Off-White

Stabilität:: Hygroscopic

CAS Datenbank: 146062-44-4

Sicherheit

Hydroxypioglitazone Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor γ (PPARγ) agonist pioglitazone (Item Nos. 71745 | 22263 | 10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to PPARγ (K_i = 1.2 μM) and activates PPARγ in a time-resolved FRET (TR-FRET) assay (EC₅₀ = 2.1 μM).

Chemische Eigenschaften

Off-White Solid

Verwenden

A metabolite of Pioglitazone (P471000).

Hydroxypioglitazone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Benzaldehyde, 4-[2-[5-[1-(methoxymethoxy)ethyl]-2-pyridinyl]ethoxy]- Ethyl-3-(2-methyl-5-pyridyl)-3-oxopropionat 5-(1-(MethoxyMethoxy)ethyl)-2-Methylpyridine 2-(5-(1-(MethoxyMethoxy)ethyl)pyridin-2-yl)ethanol 5-(4-(2-(5-(1-(MethoxyMethoxy)ethyl)pyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione 1-(6-Methylpyridin-3-yl)ethan-1-on Methyl 6-methylnicotinate

Downstream Produkte

Hydroxypioglitazone Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 85)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29860	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9642	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12373	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11922	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8615965530500	nickzhang@hangyubiotech.com	China	10986	58
Guangzhou CATO Research Chemicals Inc.	+86-020-81960175-617 +8615602392859	Intermediate@cato-chem.com	China	6335	58
DAYANG CHEM (HANGZHOU) CO.,LTD	13515810918	thtang@dycnchem.com	China	53881	58

146062-44-4()Verwandte Suche:

4'-Hydroxyacetophenon Pioglitazone Troglitazone Glichidon [5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-] thiazolidinedione hydrochloride 5-Ethylpyridin-2-ethanol 2,5-Diethylpyridin

HYDROXYPIOGLITAZONE
Hydroxy Pioglitazone (M-IV)
5-[[4-[2-[5-(1-HYDROXYETHYL)-2-PYRIDINYL]ETHOXY] PHENYL]METHYL]-2,4-THIAZOLIDINEDIONE
Pioglitazone, hydroxy M-IV
Pioglitazone Impurity 18
Hydroxy Pioglitazone Solution, 100ppm
Pioglitazone M4 Metabolite
Leriglitazone
Pioglitazone Impurity 4
2,4-Thiazolidinedione, 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-
Hydroxypioglitazone M4
146062-44-4
Sulfur & Selenium Compounds
Various Metabolites and Impurities
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals