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N-(2-PHENYLETHYL)-INDOMETHACIN AMIDE

N-(2-PHENYLETHYL)-INDOMETHACIN AMIDE Struktur
261766-32-9
CAS-Nr.
261766-32-9
Englisch Name:
N-(2-PHENYLETHYL)-INDOMETHACIN AMIDE
Synonyma:
N-2PIA;LM 4108;Indomethacin N-Phenylethyl Impurity;N-(2-PHENYLETHYL)-INDOMETHACIN AMIDE;N-(2-PHENYLETHYL)-1-P-CHLOROBENZOYL-5-METHOXY-2-METHYLINDOLE-3-ACETAMIDE;N-(2-PHENYLETHYL)-1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOLE-3-ACETAMIDE;1-(4-Chlorobenzoyl)-5-Methoxy-2-Methyl-N-(2-phenylethyl)-1H-indole-3-acetaMide;1H-Indole-3-acetamide, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-N-(2-phenylethyl)-
CBNumber:
CB2125110
Summenformel:
C27H25ClN2O3
Molgewicht:
460.95
MOL-Datei:
Mol file
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N-(2-PHENYLETHYL)-INDOMETHACIN AMIDE Eigenschaften

Siedepunkt:
640.5±55.0 °C(Predicted)
Dichte
1.22±0.1 g/cm3(Predicted)
storage temp. 
−20°C
Löslichkeit
≤80mg/ml in ethanol;10mg/ml in DMSO;14mg/ml in dimethyl formamide
pka
15.12±0.46(Predicted)
Aggregatzustand
Pale yellow solid.

Sicherheit

WGK Germany  3

N-(2-PHENYLETHYL)-INDOMETHACIN AMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

An aromatic amide of indomethacin recently reported to be a potent and selective reversible inhibitor of COX-2. Inhibits human recombinant and ovine COX-2 with IC50 of 0.06 uM and 0.125 uM, respectively

N-(2-PHENYLETHYL)-INDOMETHACIN AMIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-(2-PHENYLETHYL)-INDOMETHACIN AMIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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261766-32-9()Verwandte Suche:

6-Methoxynaphthalin-2-essigsure Naproxen Natrium-2-[(2,6-dichlor-3-methylphenyl)amino]benzoat Sulindac sulfide alpha-Methyl-4-(2-methylpropyl)-benzolessigsäure 1-Phenyl-3-pyrazolidon Indometacin Piroxicam 5-Methoxy-2-methylindol
  • N-(2-PHENYLETHYL)-1-P-CHLOROBENZOYL-5-METHOXY-2-METHYLINDOLE-3-ACETAMIDE
  • N-(2-PHENYLETHYL)-1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOLE-3-ACETAMIDE
  • N-2PIA
  • N-(2-PHENYLETHYL)-INDOMETHACIN AMIDE
  • 1-(4-Chlorobenzoyl)-5-Methoxy-2-Methyl-N-(2-phenylethyl)-1H-indole-3-acetaMide
  • LM 4108
  • Indomethacin N-Phenylethyl Impurity
  • 1H-Indole-3-acetamide, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-N-(2-phenylethyl)-
  • 261766-32-9
  • C27H25N2O3Cl
  • CyclooxygenaseEnzyme Inhibitors by Enzyme
  • A to
  • Arachidonic Acid Cascade
  • Enzyme Inhibitors
  • Inhibitors
  • Cyclooxygenase (COX) Enzymes
  • Cyclooxygenase Inhibitors
  • CyclooxygenaseCell Signaling Enzymes
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