(3R)-1-[(20S)-20-(Dimethylamino)-4β-hydroxy-5α-pregnan-3β-yl]-3-isopropylazetidin-2-one Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
This alkaloid, in which the pregnane keto group of the preceding base is reduced
to a secondary hydroxyl group, occurs in small amounts in Pachysandra termi_x0002_nalis Sieb. et Zucco It is laevorotatory having [O:]D - 18° (CHC13). Oxidation
with chromic acid yields Pachystermine A.
Einzelnachweise
Kikuchi, Uyeo., Tetrahedron Lett., 3473 (1965)
Kikuchi, Uyeo., Chern. Pharrn. Bull., 15, 549 (1967)
Partial synthesis:
Kikuchi et aZ., Tetrahedron Lett., 909 (1968)
(3R)-1-[(20S)-20-(Dimethylamino)-4β-hydroxy-5α-pregnan-3β-yl]-3-isopropylazetidin-2-one Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte