3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide

765317-72-4

CAS-Nr.: 765317-72-4

Englisch Name:: 3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide

Synonyma:: 6-BenzofuransulfonaMide, 3-(3,5-dibroMo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylaMino)sulfonyl]phenyl]-;3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]-1-benzofuran-6-sulfonamide;PTP1B-IN-4;PTP1B Inhibitor inhibitor;3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide

CBNumber:: CB22499424

Summenformel:: C26H19Br2N3O7S3

Molgewicht:: 741.45

MOL-Datei:: 765317-72-4.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 32

3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide Eigenschaften

Siedepunkt:: 855.0±75.0 °C(Predicted)

Dichte: 1.812±0.06 g/cm3(Predicted)

storage temp.: Store at -20°C, protect from light

Löslichkeit: Soluble in ethanol and DMSO

pka: 4.47±0.25(Predicted)

Aggregatzustand: Solid

Farbe: White to off-white

Sensitive: Light Sensitive

Sicherheit

3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Protein tyrosine phosphatase 1B (PTP1B) has critical roles in cell signaling relevant to diabetes, obesity, and cancer. PTP1B inhibitor is a cell-permeable allosteric inhibitor of PTP1B (IC₅₀s = 4 and 8 μM for 403 and 298 residue PTP1B forms, respectively). It binds reversibly and non-competitively, altering the conformation of the catalytic pocket. PTP1B inhibitor selectively increases the phosphorylation of the insulin receptor, insulin receptor substrate 1, and Akt, mimicking the action of insulin.

Verwenden

PTP1B Inhibitor is used as a PTP1B inhibitor blocks the activity of the Protein Tyrosine Phosphatase 1B, which is a key factor in the negative regulation of insulin and leptin signaling pathway. Protein tyrosine phosphatase 1B (PTP1B) has critical roles in cell signaling relevant to diabetes, obesity, and cancer.

3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 32)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4692	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
China Langchem Inc.	0086-21-58956006		China	7815	57

3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide
6-BenzofuransulfonaMide, 3-(3,5-dibroMo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylaMino)sulfonyl]phenyl]-
3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]-1-benzofuran-6-sulfonamide
PTP1B-IN-4
PTP1B Inhibitor inhibitor
765317-72-4
C26H19Br2N3O7S3