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1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Struktur
67469-81-2
CAS-Nr.
67469-81-2
Englisch Name:
1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE
Synonyma:
CS-1078;GBR 12935 HCl;GBR-12935 2HCL;GBR-2935(dihydrochloride);GBR 12935 DIHYDROCHLORIDE;GBR 12935 (hydrochloride);GBR 12935 dihydrochloride, >=98%;1-(2-(BENZHYDRYLOXY)ETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE.2HCL;1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride;1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE
CBNumber:
CB2351371
Summenformel:
C28H35ClN2O
Molgewicht:
451.05
MOL-Datei:
67469-81-2.mol
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1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Eigenschaften

storage temp. 
Inert atmosphere,Store in freezer, under -20°C
Löslichkeit
H2O: 20 mg/mL with warming
Aggregatzustand
powder
Farbe
white

Sicherheit

WGK Germany  3

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

A very potent and selective inhibitor of dopamine uptake

Definition

ChEBI: A hydrochloride salt that is obtained by reaction of 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine with two equivalents of hydrogen chloride. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal memb anes).

Biochem/physiol Actions

GBR 12935 inhibits the dopamine and norepinephrine transporters with Kis of 21.5 nM and 225 nM, respectively. It does not inhibit the serotonin transporter (Ki = 6.5 mM). GBR 12935 binds to a nondopaminergic piperazine site in blood platelets and brain that has been identified as cytochrome P450.

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 84)Lieferanten
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
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career henan chemical co 		+86-0371-86658258 +8613203830695
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Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
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InvivoChem 		+1-708-310-1919 +1-13798911105
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Hebei Miaoyin Technology Co.,Ltd 		+86-17367732028 +86-17367732028
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LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43348 58
Aladdin Scientific 		+1-+1(833)-552-7181
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Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131980 58

67469-81-2()Verwandte Suche:

2-(Diphenylmethoxy)-N,N-dimethyl-ethanamin Piperazindihydrochlorid 2-(Diphenylmethoxy)-N,N-dimethyl-ethanamin-hydrochlorid
  • GBR 12935 dihydrochloride, >=98%
  • GBR 12935 (hydrochloride)
  • GBR 12935 DIHYDROCHLORIDE
  • 1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE
  • GBR-12935 2HCL
  • GBR 12935 HCl
  • 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
  • Piperazine,1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)-, hydrochloride (1:2)
  • GBR-2935(dihydrochloride)
  • 1-(2-(BENZHYDRYLOXY)ETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE.2HCL
  • CS-1078
  • inhibit,Inhibitor,DAT,GBR 12935 dihydrochloride,Dopamine Transporter,SLC6A3
  • 67469-81-2
  • C28H34N2O2HCl
  • BioChemical
  • Application Index
  • Biochemicals and Reagents
  • Cell Signaling Enzymes
  • Enzymes, Inhibitors, and Substrates
  • Substrates
  • Xenobiotics and Drug Metabolism
  • Inhibitors
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