1-(2-디페닐메톡시에틸)-4-(3-페닐프로필)피페라진이염화물

1-(2-디페닐메톡시에틸)-4-(3-페닐프로필)피페라진이염화물
1-(2-디페닐메톡시에틸)-4-(3-페닐프로필)피페라진이염화물 구조식 이미지
카스 번호:
67469-81-2
한글명:
1-(2-디페닐메톡시에틸)-4-(3-페닐프로필)피페라진이염화물
동의어(한글):
1-(2-디페닐메톡시에틸)-4-(3-페닐프로필)피페라진이염화물
상품명:
1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE
동의어(영문):
CS-1078;GBR 12935 HCl;GBR-12935 2HCL;GBR-2935(dihydrochloride);GBR 12935 DIHYDROCHLORIDE;GBR 12935 (hydrochloride);GBR 12935 dihydrochloride, >=98%;1-(2-(BENZHYDRYLOXY)ETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE.2HCL;1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride;1-(2-DIPHENYLMETHOXYETHYL)-4-(3-PHENYLPROPYL)PIPERAZINE DIHYDROCHLORIDE
CBNumber:
CB2351371
분자식:
C28H35ClN2O
포뮬러 무게:
451.05
MOL 파일:
67469-81-2.mol

1-(2-디페닐메톡시에틸)-4-(3-페닐프로필)피페라진이염화물 속성

저장 조건
Inert atmosphere,Store in freezer, under -20°C
용해도
H2O: 20 mg/mL(가온 시)
물리적 상태
가루
색상
하얀색

안전

WGK 독일 3

1-(2-디페닐메톡시에틸)-4-(3-페닐프로필)피페라진이염화물 C화학적 특성, 용도, 생산

용도

A very potent and selective inhibitor of dopamine uptake

정의

ChEBI: A hydrochloride salt that is obtained by reaction of 1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine with two equivalents of hydrogen chloride. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal memb anes).

Biochem/physiol Actions

GBR 12935 inhibits the dopamine and norepinephrine transporters with Kis of 21.5 nM and 225 nM, respectively. It does not inhibit the serotonin transporter (Ki = 6.5 mM). GBR 12935 binds to a nondopaminergic piperazine site in blood platelets and brain that has been identified as cytochrome P450.

1-(2-디페닐메톡시에틸)-4-(3-페닐프로필)피페라진이염화물 준비 용품 및 원자재

원자재

준비 용품


1-(2-디페닐메톡시에틸)-4-(3-페닐프로필)피페라진이염화물 공급 업체

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