디펜히드라민
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디펜히드라민 속성
- 녹는점
- 167-172°C
- 끓는 점
- bp2.0 150-165°
- 밀도
- 0.9889 (rough estimate)
- 굴절률
- 1.5450 to 1.5490
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 기름
- 산도 계수 (pKa)
- pKa 9.1 (Uncertain)
- 색상
- 오일과 같은 색상
- Merck
- 14,3309
- BCS Class
- 1
- CAS 데이터베이스
- 58-73-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| RTECS 번호 | KR6825000 | ||
|---|---|---|---|
| HS 번호 | 2922.19.7000 | ||
| 유해 물질 데이터 | 58-73-1(Hazardous Substances Data) | ||
| 독성 | LD50 oral in rat: 390mg/kg |
디펜히드라민 C화학적 특성, 용도, 생산
개요
Diphenhydramine is one of the main representatives of antihistamine drugs that block H1 receptors. Besides antihistamine activity, diphenhydramine exhibits a local anesthetic effect, relaxes smooth muscle, and has sedative and soporific action.용도
Diphenhydramine also reduces muscle rigidity and general stiffness, and has a relatively minor effect on tremors.색상 색인 번호
This antihistaminic drug with sedative properties is mainly sold over the counter. It can be used both topically (treatment of pruritis) and orally for its antiallergic, antiemetic, sedative, and anticough properties. Allergic or photoallergic contact dermatitis and fixeddrug eruption seem to be rare.Safety Profile
Deadly human poison by an unspecified route. Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Experimental reproductive effects. Human systemic effects by ingestion: somnolence, alteration of operant conditioning, changes in psychophysiological tests. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO,. See also ETHERS.환경귀착
Diphenhydramine is fairly stable in the environment although it does undergo photodegradation. Conjugates of diphenhydramine such as diphenhydramine-N-glucuronide may be converted back to the parent compound, diphenhydramine, through enzymatic cleavage during sewage treatment process. Diphenhydramine is removed poorly through wastewater treatment processes and is found in significant concentrations in aquatic organisms downstream from such plants.Diphenhydramine has significant risk for bioaccumulation, particularly in water downstream from wastewater and sewage treatment facilities.
Solubility in water
One gram of diphenhydramine is soluble in 1 mL of water, 2 mL of ethanol, 2 mL of chloroform, or 50 mL of acetone; the compound is very slightly soluble in benzene or ether.디펜히드라민 준비 용품 및 원자재
원자재
벤질 알코올
에틸렌 클로로히드린
디메틸아민
디페닐메탄
탄산나트륨(경회)
N,N-디메틸-2-(벤질옥시)에탄아민
2-(디페닐메톡시)-N-메틸에틸아민
Diphenhydramine
염산디펜히드라민
벤즈히드릴클로라이드
2-디메틸아미노에탄올
2-Chloroethyldimethylamine
벤즈히드롤
준비 용품
디펜히드라민 공급 업체
글로벌( 280)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 6011 | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 |
Sara@xmwonderfulbio.com | China | 305 | 58 |
| Hebei Anlijie Biotechnology Co., Ltd | +8619031013551 |
ably@aljbio.com | China | 196 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 19368 | 58 |
| Sigma Audley | +86-18336680971 +86-18126314766 |
nova@sh-teruiop.com | China | 525 | 58 |
| Shanghai Aosiris new Material Technology Co., LTD | 86-15139564871 +8615139564871 |
wrjmoon2000@163.com | China | 357 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21687 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9340 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 |
kaia@neputrading.com | China | 1011 | 58 |