KENDOMYCIN

183202-73-5

CAS-Nr.: 183202-73-5

Englisch Name:: KENDOMYCIN

Synonyma:: kendomycin from streptomyces violaceoruber;1,19:5,9-Diepoxybenzocyclooctadecen-3(5H)-one, 6,7,8,9,10,11,12,15,16,17,18,19-dodecahydro-4,7,19-trihydroxy-2,6,8,12,14,16,18-heptamethyl-, (5R,6R,7S,8R,9R,12S,13E,16S,18S,19S)-

CBNumber:: CB2503707

Summenformel:: C29H42O6

Molgewicht:: 486.64

MOL-Datei:: 183202-73-5.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 23

KENDOMYCIN Eigenschaften

Schmelzpunkt:: 236-240℃

Siedepunkt:: 678.5±55.0 °C(Predicted)

Dichte: 1.19±0.1 g/cm3(Predicted)

storage temp.: −20°C

Löslichkeit: Soluble in DMSO

Aggregatzustand: solid

pka: 8.53±0.70(Predicted)

Farbe: Yellow

Sicherheit

S-Sätze:	22-24/25
WGK Germany	3

KENDOMYCIN Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Beschreibung

Kendomycin is a macrolide from Streptomyces which displays potent cytotoxicity against several carcinoma cell lines (GI₅₀ < 100 nM). It also acts as an endothelin receptor antagonist and has antiosteoporotic activities. Certain effects are thought to be mediated through inhibition of proteasomal degradation of proteins.

Verwenden

Kendomycin is an unusual macrocyclic metabolite containing a rare quinone methide group. Kendomycin is a potent antibacterial agent against Gram positive and Gram negative bacteria, including MRSA strains, also displaying antitumour activity. Kendomycin is a potent endothelin receptor agonist and demonstrates antiosteoporotic activity.

KENDOMYCIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

KENDOMYCIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 23)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19743	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Shanghai Tauto Biotech Co., Ltd.	021-51320588	tauto@tautobiotech.com	China	3989	66
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	isunpharm@qq.com	China	4428	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9707	58
Lynnchem	86-(0)29-85992781 17792393971	info@lynnchem.com	China	4587	58
Novachemistry	44-20819178-90 02081917890	info@novachemistry.com	United Kingdom	4381	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	56070	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58

kendomycin from streptomyces violaceoruber
1,19:5,9-Diepoxybenzocyclooctadecen-3(5H)-one, 6,7,8,9,10,11,12,15,16,17,18,19-dodecahydro-4,7,19-trihydroxy-2,6,8,12,14,16,18-heptamethyl-, (5R,6R,7S,8R,9R,12S,13E,16S,18S,19S)-
183202-73-5
C29H42O6