켄도마이신

켄도마이신
켄도마이신 구조식 이미지
카스 번호:
183202-73-5
한글명:
켄도마이신
동의어(한글):
켄도마이신
상품명:
KENDOMYCIN
동의어(영문):
kendomycin from streptomyces violaceoruber;1,19:5,9-Diepoxybenzocyclooctadecen-3(5H)-one, 6,7,8,9,10,11,12,15,16,17,18,19-dodecahydro-4,7,19-trihydroxy-2,6,8,12,14,16,18-heptamethyl-, (5R,6R,7S,8R,9R,12S,13E,16S,18S,19S)-
CBNumber:
CB2503707
분자식:
C29H42O6
포뮬러 무게:
486.64
MOL 파일:
183202-73-5.mol

켄도마이신 속성

녹는점
236-240℃
끓는 점
678.5±55.0 °C(Predicted)
밀도
1.19±0.1 g/cm3(Predicted)
저장 조건
−20°C
용해도
DMSO에 용해됨
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
8.53±0.70(Predicted)
색상
노란색

안전

안전지침서 22-24/25
WGK 독일 3

켄도마이신 C화학적 특성, 용도, 생산

개요

Kendomycin is a macrolide from Streptomyces which displays potent cytotoxicity against several carcinoma cell lines (GI50 < 100 nM). It also acts as an endothelin receptor antagonist and has antiosteoporotic activities. Certain effects are thought to be mediated through inhibition of proteasomal degradation of proteins.

용도

Kendomycin is an unusual macrocyclic metabolite containing a rare quinone methide group. Kendomycin is a potent antibacterial agent against Gram positive and Gram negative bacteria, including MRSA strains, also displaying antitumour activity. Kendomycin is a potent endothelin receptor agonist and demonstrates antiosteoporotic activity.

켄도마이신 준비 용품 및 원자재

원자재

준비 용품


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