N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Pale yellow powder
Verwenden
N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthese
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450Kg of concentrated sulfuric acid was added to the reactor, the temperature of the reaction solution was room temperature, the reaction solution containing the intermediate 1 was slowly added dropwise, and after sufficient stirring, 75 kg of 70% nitric acid was slowly added. After stirring until completion of the reaction, 800kg of crushed ice was added to the reaction solution and stirred constantly , Finally, pH was adjusted to 7~8 with ammonia solution to give crude product after filtration, crude product was recrystallized from methyl ethyl ketone to give 140 Kg of Intermediate 2, with a yield of 81.5%.
N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte