N-アセチル-2-(4-ニトロフェニル)エチルアミン 化学特性,用途語,生産方法
外観
白色~ほとんど白色粉末~結晶
化学的特性
Pale yellow powder
使用
N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
合成
![3.png 説明図](/NewsImg/2022-03-15/6378295968459400055559967.jpg)
450Kg of concentrated sulfuric acid was added to the reactor, the temperature of the reaction solution was room temperature, the reaction solution containing the intermediate 1 was slowly added dropwise, and after sufficient stirring, 75 kg of 70% nitric acid was slowly added. After stirring until completion of the reaction, 800kg of crushed ice was added to the reaction solution and stirred constantly , Finally, pH was adjusted to 7~8 with ammonia solution to give crude product after filtration, crude product was recrystallized from methyl ethyl ketone to give 140 Kg of Intermediate 2, with a yield of 81.5%.
N-アセチル-2-(4-ニトロフェニル)エチルアミン 上流と下流の製品情報
原材料
準備製品