ANTI-HIF-1ALPHA
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- CAS-Nr.
- Englisch Name:
- ANTI-HIF-1ALPHA
- Synonyma:
- ANTI-HIF-1ALPHA;Anti-ARNT protein 2;ANTI-HIF-1ALPHA, HUMAN;ANTI-HIF-1ALPHA (C-TERM);ANTI-HIF-1ALPHA MOUSE MAB;MONOCLONAL ANTI-HIF-1ALPHA;ANTI-HYPOXIA-INDUCIBLE FACTOR-1ALPHA;Anti-HIF1A antibody produced in rabbit;Anti-ARNT2 antibody produced in rabbit;ANTI-HYPOXIA-INDUCIBLE FACTOR 1ALPHA, HUMAN
- CBNumber:
- CB3404863
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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ANTI-HIF-1ALPHA Eigenschaften
- storage temp.
- -20°C
- Aggregatzustand
- buffered aqueous solution
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
| H412 |
Schädlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gewässergefährdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P272 |
Kontaminierte Arbeitskleidung nicht außerhalb des Arbeitsplatzes tragen. |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P333+P313 |
Bei Hautreizung oder -ausschlag: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
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ANTI-HIF-1ALPHA Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Rabbit polyclonal anti-HIF1A antibody is used to tag hypoxia-inducible factor 1 α for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques such as immunoblotting, immunoprecipitation, and immunofluorescence. It is used as a probe to determine the presence and roles of hypoxia-inducible factor 1 α in the structure and function of hypoxia-inducible factor 1.
Allgemeine Beschreibung
The gene encoding HIF1A (hypoxia inducible factor 1 subunit α) is localized on human chromosome 14q23.2. It is part of the HIF-1 heterodimer complex and is modulated by oxygen.
Biochem/physiol Actions
Hypoxia-inducible factor-1(HIF1) plays an essential role in cellular and systemic homeostatic responses to hypoxia. During hypoxia, the two subunits of this factor undergo post-translational modifications which in turn promote transactivation. HIF-1α gene loss is associated with development of nonpapillary renal carcinomas. The encoded protein functions as a key regulator of the vascular endothelial growth factor (VEGF) under hypoxic response in human stromal cells in vitro. HIF-1α protein expression is often seen in invasive breast cancer. Experimental data demonstrates that downregulation of HIF-1α decreases tumorigenicity of MCF-7 (human breast adenocarcinoma cell line) cells and propose a promising combination of both anti-HIF-1 strategy and traditional chemotherapy to improve cancer treatment.
ANTI-HIF-1ALPHA Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ANTI-HIF-1ALPHA Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 12)Lieferanten
- MOUSE ANTI-HUMAN/MOUSE/RAT/FERRET/SHEEP HIF1ALPHA
- MOUSE ANTI-HUMAN/MOUSE/RAT/FERRET/SHEEP HYPOXIA INDUCIBLE FACTOR 1 ALPHA
- MONOCLONAL ANTI-HYPOXIA INDUCIBLE FACTOR 1, ALPHA SUBUNIT
- MONOCLONAL ANTI-HIF-1ALPHA
- ANTI-HYPOXIA-INDUCIBLE FACTOR-1ALPHA
- ANTI-HYPOXIA INDUCIBLE FACTOR 1ALPHA (C-TERM)
- ANTI-HYPOXIA-INDUCIBLE FACTOR 1ALPHA, HUMAN
- ANTI-HYPOXIA-INDUCIBLE FACTOR 1ALPHA, HUMAN (MOUSE)
- ANTI-HYPOXIA-INDUCIBLE FACTOR 1ALPHA MOUSE MAB
- ANTI-HYPOXIA INDUCIBLE FACTOR-1, ALPHA SUBUNIT
- ANTI-HIF-1ALPHA
- ANTI-HIF-1ALPHA (C-TERM)
- ANTI-HIF-1ALPHA, HUMAN
- ANTI-HIF-1ALPHA MOUSE MAB
- Anti-Hypoxia Inducible Factor 1, α subunit
- Monoclonal Anti-HIF-1α antibody produced in mouse
- Anti-ARNT-interacting protein antibody produced in rabbit
- Anti-Basic-helix-loop-helix-PAS protein MOP1 antibody produced in rabbit
- Anti-HIF1A antibody produced in rabbit
- Anti-Member of PAS protein 1 antibody produced in rabbit
- Anti-ARNT protein 2
- Anti-ARNT2 antibody produced in rabbit
- Anti-Aryl hydrocarbon receptor nuclear translocator 2
