Ginsenoside Rh2
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- CAS-Nr.
- 78214-33-2
- Englisch Name:
- Ginsenoside Rh2
- Synonyma:
- 20(S)-Rh2;GINSENOSIDE RH2;GINSENOSIDE Rh2(SH);Ginsenoside Rh2 ,98%;3β-(β-D-Glucopyranosyl;R-form-Ginsenoside Rh2;Ginsenoside Rh2, 20(S)-;Ginsenoside Rh2 USP/EP/BP;dihydroxydammar-24-en-3-yl;β-D-Glucopyranoside, (3β,12β)-12,20-
- CBNumber:
- CB3728899
- Summenformel:
- C36H62O8
- Molgewicht:
- 622.88
- MOL-Datei:
- 78214-33-2.mol
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Ginsenoside Rh2 Eigenschaften
- Schmelzpunkt:
- 139-144 °C
- Siedepunkt:
- 726.4±60.0 °C(Predicted)
- Dichte
- 1.19±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- Löslichkeit
- DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
- Aggregatzustand
- Solid
- pka
- 12.91±0.70(Predicted)
- Farbe
- White
- InChIKey
- CKUVNOCSBYYHIS-IRFFNABBSA-N
- LogP
- 5.620 (est)
- CAS Datenbank
- 78214-33-2(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher |
Xn |
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R-Sätze: |
22 |
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S-Sätze: |
24/25 |
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WGK Germany |
3 |
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RTECS-Nr. |
LZ5776539 |
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HS Code |
29389090 |
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Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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Sicherheit |
P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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Ginsenoside Rh2 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Ginsenoside Rh
2 is a steroid glycoside found in plants of the genus
Panax that has diverse biological activities. It inhibits release of β-hexosaminidase from RBL-2H3 cells (IC
50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a dose of 25 mg/kg. It inhibits growth of HRA ovarian and BxPC-3 pancreatic cancer cells in a dose-dependent manner.
In vivo, ginsenoside Rh
2 decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma. Ginsenoside Rh
2 also reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury.
Chemische Eigenschaften
White solid
Verwenden
20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro.
Definition
ChEBI: A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3
has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.
Ginsenoside Rh2 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Ginsenoside Rh2 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 269)Lieferanten
78214-33-2()Verwandte Suche:
- b-D-Glucopyranoside, (3b,12b)-12,20-dihydroxydaMMar-24-en-3-yl
- (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl-β-D-glucopyranoside
- Ginsenoside Rh2, 20(S)-
- (3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl beta-d-glucopyranoside
- GINSENOSIDE RH2
- dihydroxydammar-24-en-3-yl
- β-D-Glucopyranoside, (3β,12β)-12,20-
- R-form-Ginsenoside Rh2
- 12β,20-Dihydroxy-5α-dammar-24-en-3β-yl β-D-glucopyranoside
- 3β-(β-D-Glucopyranosyloxy)dammara-24-ene-12β,20-diol
- 3β-(β-D-Glucopyranosyl
- GINSENOSIDE Rh2(SH)
- Ginsenoside Rh2 ,98%
- 20(S)-Rh2
- Natural Plant Extracts Ginsenoside Rh2 HPLC 15% 50% 98% 78214-33-2
- 2-[[12-hydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
- β-D-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl
- Ginsenoside Rh2 USP/EP/BP
- (2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
- 78214-33-2
- C36H62O8
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Inhibitors
- Ginsenoside series
- 78214-33-2