(3β,6α,12β)-3,12-Dihydroxydammar-24-en-6,20-diylbis[β-D-glucopyranosid]
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- CAS-Nr.
- 22427-39-0
- Bezeichnung:
- (3β,6α,12β)-3,12-Dihydroxydammar-24-en-6,20-diylbis[β-D-glucopyranosid]
- Englisch Name:
- Ginsenoside Rg1
- Synonyma:
- Rg1;SANCHINOSIDE C1;PANAXOSIDE A;ginsenosidea2;ginsenosideg1;panaxosiderg1;Gensenoside Rg1;GINSENOSIDE RGL;GINSENOSIDE RG1;Panaxsaponin Rg1
- CBNumber:
- CB7331840
- Summenformel:
- C42H72O14
- Molgewicht:
- 801.01
- MOL-Datei:
- 22427-39-0.mol
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(3β,6α,12β)-3,12-Dihydroxydammar-24-en-6,20-diylbis[β-D-glucopyranosid] Eigenschaften
- Schmelzpunkt:
- 194～197℃
- Siedepunkt:
- 898.5±65.0 °C(Predicted)
- Dichte
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
- pka
- 12.91±0.70(Predicted)
- Farbe
- White to Off-White
- Stabilität:
- Hygroscopic
- InChIKey
- YURJSTAIMNSZAE-OLCOBRLXNA-N
- LogP
- 1.670 (est)
- CAS Datenbank
- 22427-39-0(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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(3β,6α,12β)-3,12-Dihydroxydammar-24-en-6,20-diylbis[β-D-glucopyranosid] Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S2:Darf nicht in die Hände von Kindern gelangen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Beschreibung
Ginsenoside RG1(Rg1) is a natural product found in Panax notoginseng, Panax ginseng, and Panax vietnamensis. It is one of the primary bioactive ingredients in Panax notoginseng saponins. Numerous studies have indicated that Rg1 plays significant roles in health benefits such as anticancer, neuroprotective, anti-senescence, anti-inflammation, and antioxidative effects. Also, extensive research has demonstrated that Rg1 is associated with various diseases, including cardiovascular disease, Alzheimer’s disease, spinal cord injury, and liver injury. Xue et al. and Yu et al. demonstrated that Rg1 ameliorated streptozotocin-induced oxidative stress and myocardial apoptosis and suppressed HG-induced mesenchymal activation and fibrosis[1].
Chemische Eigenschaften
White solid
Verwenden
Ginsenoside Rg1 protects against arthitis through osteoclast differentiation inhibition. Anti-tumor agent, inhibits the NF-kB-dependant MMP-expression in PMA (phorbol myristate acetate)-induced tumor cell invasion.
Definition
ChEBI: A ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 <ital pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-glucopyranosides, and in which a double bond has been introduced at the 24-25 posit on.
(3β,6α,12β)-3,12-Dihydroxydammar-24-en-6,20-diylbis[β-D-glucopyranosid] Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(3β,6α,12β)-3,12-Dihydroxydammar-24-en-6,20-diylbis[β-D-glucopyranosid] Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 363)Lieferanten
22427-39-0((3β,6α,12β)-3,12-Dihydroxydammar-24-en-6,20-diylbis[β-D-glucopyranosid])Verwandte Suche:
2-O-β-D-Glucopyranosyl-(3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl-β-D-glucopyranosid
GINSENOSIDE RE
Ginsenoside Rg2
Ginseng extract
Ginsenoside rb1
Ginsenoside Rh2
GinsenosideRo
2-O-(6-Desoxy-α-L-mannopyranosyl)-(3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl-β-D-glucopyranosid
TRIBULOSIDE
20-[(6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyl)oxy]-12β-hydroxydammar-24-en-3β-yl-2-O-β-D-glucopyranosyl-β-D-glucopyranosid
20-[(6-O-α-L-Arabinofuranosyl-β-D-glucopyranosyl)oxy]-12β-hydroxydammar-24-en-3β-yl-2-O-β-D-glucopyranosyl-β-D-glucopyranosid
Saponine
3,3,5,5-Tetramethylcyclohexanol
(1S-(1α,2β,5beta))-5-Methyl-(1-isopropyl)cyclohexan-2-ol
20(R)-Propanaxadiol
Ginsenosides
(3β,6α,12β)-3,12-Dihydroxydammar-24-en-6,20-diylbis[β-D-glucopyranosid]
- (3b,6a,12b)-3,12-dihydroxydammar-24-ene-6,20- diylbis(beta-d-glucopyranoside)
- (3beta,6alpha,12beta)-3,12-dihydroxydammar-24-ene-6,20-diylbis[beta-D-glucopyranoside]
- Ginsenoside Rg1 std.
- Ginsenoside Rg1 (CAS# 22427-39-0)
- Gensenoside Rg1
- GINSENOSIDE RG1 WITH HPLC
- GINSENOSIDE-RG1 (GINSENOSIDE A2: GINSENOSIDE G1)
- dihydroxydammar-24-ene-6,20-diylbis-
- β-D-Glucopyranoside, (3β,6α,12β)-3,12-
- (3β,6α,12β)-3,12-Dihydroxydammar-24-ene-6,20-diyl bis-β-D-glucopyranoside
- [3β,12β-Dihydroxy-5α-dammar-24-ene-6α,20-diyl]bis(β-D-glucopyranoside)
- 20-(β-D-Glucopyranosyloxy)-3β,12β-dihydroxy-5α-dammara-24-ene-6α-yl β-D-glucopyranoside
- 3β,12β-Dihydroxy-5α-dammar-24-ene-6α,20-diylbis(β-D-glucopyranoside)
- Ginsenoside Rg1 ,98%
- Ginsenoside Rg1(Sanchinoside C1)
- Ginsenoside Rg1 (saponin of Panax ginseng)
- (6)-beta-d-glucopyranosyl-(20)-beta-d-glucopyranosyl-20s-protopanaxatriol
- ginsenosidea2
- ginsenosideg1
- panaxosiderg1
- DaMMarane, β-D-glucopyranoside deriv.
- Panaxoside A(7CI)
- Panaxsaponin Rg1
- PANAXOSIDE A
- SANCHINOSIDE C1,PANAXOSIDE A
- GINSENOSIDE RGL
- GINSENOSIDE RG1
- Ginsenoside Rg1, >=99%
- Ginsenoside Rg1, 98%, from Panax ginseng C. A. Mey.
- Ginsenoside Rg1 22427-39-0
- Ginsenoside Rg1 RS
- Ginsenoside Rg1 Standard
- β-D-Glucopyranoside, (3β,6α,12β)-3,12-dihydroxydammar-24-ene-6,20-diyl bis-
- (2R,3R,4S,5S,6R)-2-(((3S,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-6-y
- 20-(beta-D-Glucopyranosyloxy)-3beta,12beta-dihydroxydammar-24-en-6alpha-yl beta-D-Glucopyranoside
- Ginsenoside Rg1 (10mM in DMSO)
- (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
- Rg1
- SANCHINOSIDE C1
- Ginsenoside Rg1 (8CI)
- Ginsenoside Rg1 reference substance
- 22427-39-0
- 11021-41-0
- The group of Ginsenosides
- Saponins
- Inhibitors
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Ginsenoside series
