Dotinurad

Dotinurad Struktur
1285572-51-1
CAS-Nr.
1285572-51-1
Englisch Name:
Dotinurad
Synonyma:
Dotinurad;Dotinurad (FYU-981);3-(3,5-dichloro-4-hydroxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole;(3,5-Dichloro-4-hydroxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)methanone;(3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone;Methanone, (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)-;uricosuric,Inhibitor,Dotinurad,URAT1,urate,reabsorption,SLC22A12,Urate transporter 1,inhibit,transporter
CBNumber:
CB44667832
Summenformel:
C14H9Cl2NO4S
Molgewicht:
358.2
MOL-Datei:
1285572-51-1.mol

Dotinurad Eigenschaften

Schmelzpunkt:
188 - 191°C
Siedepunkt:
614.8±55.0 °C(Predicted)
Dichte
1.662±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
Löslichkeit
Chloroform (Slightly, Sonicated), DMSO (Sparingly)
pka
4.60±0.25(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White

Sicherheit

Dotinurad Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Dotinurad is an organic compound with the chemical Name (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone. This compound is a newer urate-lowering agent that suppresses uric acid reabsorption through the selective inhibition of urate transporter 1 (URAT1) in the proximal renal tubules, and it was first approved in Japan in 2020 for the treatment of hyperuricemia, irrespective of gout[1].

Verwenden

Dotinurad is a useful drug for treating hyperuricemia and gout.

Dotinurad Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dotinurad Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 64)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
Henan Alfa Chemical Co., Ltd
+8618339805032
alfa4@alfachem.cn China 13094 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439
sales@nextpeptide.com China 19915 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6393 58
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd.
+86-029-86185165 +8618629664246
guoyuan@eastchinapharm.com China 1615 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49739 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152
Mandy@hangyubiotech.com China 10978 58
Arizest(Shanghai)Pharmatech Co., Ltd
+86-021-60753300
3652837972@qq.com China 220 58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
+86-18600796368 +86-18600796368
sales@sjar-tech.com China 49 58
Wuhan HSN Pharmaresearch CO., LTD. 027-63499089 18086100502
linwell@126.com China 201 50

  • Dotinurad
  • Methanone, (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)-
  • Dotinurad (FYU-981)
  • (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone
  • uricosuric,Inhibitor,Dotinurad,URAT1,urate,reabsorption,SLC22A12,Urate transporter 1,inhibit,transporter
  • (3,5-Dichloro-4-hydroxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)methanone
  • 3-(3,5-dichloro-4-hydroxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole
  • 1285572-51-1
  • API
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