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Dotinurad

Dotinurad 구조식 이미지

카스 번호:: 1285572-51-1

상품명:: Dotinurad

동의어(영문):: Dotinurad;Dotinurad (FYU-981);3-(3,5-dichloro-4-hydroxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole;(3,5-Dichloro-4-hydroxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)methanone;(3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone;Methanone, (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxido-3(2H)-benzothiazolyl)-;uricosuric,Inhibitor,Dotinurad,URAT1,urate,reabsorption,SLC22A12,Urate transporter 1,inhibit,transporter

CBNumber:: CB44667832

분자식:: C14H9Cl2NO4S

포뮬러 무게:: 358.2

MOL 파일:: 1285572-51-1.mol

속성

안전

용도

공급 업체 68

Dotinurad 속성

녹는점: 188 - 191°C

끓는 점: 614.8±55.0 °C(Predicted)

밀도: 1.662±0.06 g/cm3(Predicted)

저장 조건: -20°C Freezer, Under inert atmosphere

용해도: 클로로포름(약간 용해됨, 초음파 처리), DMSO(약간 용해됨)

산도 계수 (pKa): 4.60±0.25(Predicted)

물리적 상태: 고체

물리적 상태: 단단한 모양

색상: 흰색에서 황백색까지

InChI: InChI=1S/C14H9Cl2NO4S/c15-9-5-8(6-10(16)13(9)18)14(19)17-7-22(20,21)12-4-2-1-3-11(12)17/h1-6,18H,7H2

InChIKey: VOFLAIHEELWYGO-UHFFFAOYSA-N

SMILES: C(C1=CC(Cl)=C(O)C(Cl)=C1)(N1C2=CC=CC=C2S(=O)(=O)C1)=O

안전

Dotinurad C화학적 특성, 용도, 생산

개요

Dotinurad is an organic compound with the chemical Name (3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone. This compound is a newer urate-lowering agent that suppresses uric acid reabsorption through the selective inhibition of urate transporter 1 (URAT1) in the proximal renal tubules, and it was first approved in Japan in 2020 for the treatment of hyperuricemia, irrespective of gout[1].

용도

Dotinurad is a useful drug for treating hyperuricemia and gout.

Dotinurad 준비 용품 및 원자재

원자재

준비 용품

Dotinurad 공급 업체

글로벌( 68)공급 업체

공급자	전화	이메일	국가	제품 수	이점
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.	+86-18600796368 +86-18600796368	sales@sjar-tech.com	China	123	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Henan Alfa Chemical Co., Ltd	+8618339805032	alfa4@alfachem.cn	China	13187	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd.	+86-029-86185165 +8618629664246	guoyuan@eastchinapharm.com	China	1615	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	10978	58
Arizest(Shanghai)Pharmatech Co., Ltd	+86-021-60753300	3652837972@qq.com	China	220	58
Wuhan HSN Pharmaresearch CO., LTD.	027-63499089 18086100502	linwell@126.com	China	201	50

Dotinurad 관련 검색:

Dotinurad Impurity 1 Dotinurad Impurity 11 Dotinurad Impurity 13 Dotinurad Impurity 5 Dotinurad Impurity 2 Methanone, 3(2H)-benzothiazolyl(3,5-dichloro-4-methoxyphenyl)- Dotinurad Impurity 6 Dotinurad Impurity 20 Dotinurad Impurity 14 Dotinurad Impurity 9 Dotinurad Impurity 4 Dotinurad Impurity 17 Dotinurad Impurity 12 Dotinurad Impurity 21 Dotinurad Impurity 16 Dotinurad Impurity 8 Dotinurad Impurity 3 Dotinurad Impurity 10