Naratriptan Hydrochloride

Naratriptan Hydrochloride Struktur
143388-64-1
CAS-Nr.
143388-64-1
Englisch Name:
Naratriptan Hydrochloride
Synonyma:
Naramig;Amerge.;GR-85548A;Nariptan Hydrochloride;Naratriptan Nitrate USP;GR-85548A hydrochloride;Naratriptan Hydrochloride;Naratryptan hydrochloride;Naratriptan monohydrochloride;Naratriptan HCl (GR-85548A HCl)
CBNumber:
CB4500391
Summenformel:
C17H25N3O2S.ClH
Molgewicht:
371.93
MOL-Datei:
143388-64-1.mol

Naratriptan Hydrochloride Eigenschaften

Schmelzpunkt:
234-236°C
storage temp. 
-20°C Freezer
Löslichkeit
H2O: ≥10mg/mL
Aggregatzustand
powder
Farbe
white to off-white
InChIKey
AWEZYKMQFAUBTD-UHFFFAOYSA-N
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xi
R-Sätze: 36
S-Sätze: 26
WGK Germany  3
HS Code  2935904000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Naratriptan Hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Naramig was launched in Germany, Sweden and the UK for use in migraine. It is chemically available via a number of related synthetic routes all having about three steps starting from 5-bromoindole. It is a new serotonin 5-HT1B/1D receptor antagonist with modest affinity for 5-HT1a, and very weak affinity for 5-HT3 receptors. It has little or no affinity for a wide range of non-serotonin receptors including a- and padrenoceptors, dopamine, neurokinin NK1, and opiate receptors. It mediates vasoconstriction in cerebral vasculature (extra cerebral intracranial vessels), reduces neurogenic inflammation, and inhibits responses mediated by the trigeminal nerves. It has a 6- and 3-fold greater affinity for 5-HT1B, and 5-HT1D, receptors, respectively, than sumatriptan which translates to a 2-3 fold increase in potency. The reoccurance of headache was less compared to sumatriptan, zolmitriptan and rizatriptan. Naramig had no clinical effects on blood pressure or heart rate, had a long duration of action with very good tolerability, and has high oral bioavailability.

Chemische Eigenschaften

Beige Solid

Verwenden

Naratriptan Hydrochloride is a triptan drug and is used for the treatment of migraine headaches

Naratriptan Hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Naratriptan Hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 163)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806
sales@capotchem.com China 29798 60
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075
jack.li@time-chemicals.com China 1807 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29897 58
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 967 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39916 58
TopScience Biochemical
00852-68527855
info@itopbiochem.com China Hong Kong 902 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49391 58
WinWin Chemical CO., Limited
+86-0577-64498589 +8615325081899
sales@win-winchemical.com China 14197 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
sales@hzclap.com CHINA 6313 58

143388-64-1()Verwandte Suche:


  • NARATRIPTAN HYDROCHLORIDE (125 MG)F0C3600.998MG/MG(AI)
  • Amerge.
  • Naramig
  • Naratriptan Hydrochloride
  • N-Methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide Hydrochloride
  • N-Methyl-3-(1-methylpiperidin-4-yl)-1H-indole-5-ethanesulfonamide hydrochloride
  • Naratriptan monohydrochloride
  • Naratriptan Hydrochloride (125 mg)
  • 1H-Indole-5-ethanesulfonaMide,N-Methyl-3-(1-Methyl-4-piperidinyl
  • N-Methyl-2-(3-(1-Methylpiperidin-4-yl)-1H-indol-5-yl)ethanesulfonaMide hydrochloride
  • Nariptan Hydrochloride
  • Naratriptan Nitrate USP
  • 1H-Indole-5-ethanesulfonaMide,N-Methyl-3-(1-Methyl-4-piperidinyl)-, hydrochloride (1:1)
  • GR-85548A
  • N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide hydrochloride
  • 1H-Indole-5-ethanesulfonamide,N-methyl-3-(1-methyl-4-piperidinyl)-,hydrochloride
  • NARATRIPTAN HYDROCHLORIDE (125 MG)F0C36099%8MG/MG(AI)
  • GR-85548A hydrochloride
  • Naratriptan Hydrochloride USP/EP/BP
  • Naratryptan hydrochloride
  • Naratriptan HCl (GR-85548A HCl)
  • Naratriptan HydrochlorideQ: What is Naratriptan Hydrochloride Q: What is the CAS Number of Naratriptan Hydrochloride Q: What is the storage condition of Naratriptan Hydrochloride
  • Naratriptan Hydrochloride (1457469)
  • N-Methyl-2-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)ethane-1-sulfonamide hydrochloride
  • 143388-64-1
  • C17H25N3O2SHCl
  • C17H25N3O2SClH
  • C17H26ClN3O2S
  • Amerge, Naramig
  • Pharmaceuticals
  • Inhibitors
  • APIs
  • Intermediates & Fine Chemicals
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