Naratriptan Hydrochloride
- CAS No.
- 143388-64-1
- Chemical Name:
- Naratriptan Hydrochloride
- Synonyms
- Naramig;Amerge.;GR-85548A;Nariptan Hydrochloride;Naratriptan Nitrate USP;GR-85548A hydrochloride;Naratriptan Hydrochloride;Naratryptan hydrochloride;Naratriptan monohydrochloride;Naratriptan HCl (GR-85548A HCl)
- CBNumber:
- CB4500391
- Molecular Formula:
- C17H25N3O2S.ClH
- Molecular Weight:
- 371.93
- MDL Number:
- MFCD08141821
- MOL File:
- 143388-64-1.mol
| Melting point | 234-236°C |
|---|---|
| storage temp. | -20°C Freezer |
| solubility | H2O: ≥10mg/mL |
| form | powder |
| color | white to off-white |
| InChIKey | AWEZYKMQFAUBTD-UHFFFAOYSA-N |
| FDA UNII | 10X8X4P12Z |
Naratriptan Hydrochloride price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N1415 | Naratriptan hydrochloride ≥98% (HPLC) | 143388-64-1 | 10mg | $86 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1457469 | Naratriptan hydrochloride United States Pharmacopeia (USP) Reference Standard | 143388-64-1 | 125mg | $581 | 2024-03-01 | Buy |
| TCI Chemical | N1153 | Naratriptan Hydrochloride | 143388-64-1 | 50MG | $174 | 2024-03-01 | Buy |
| TCI Chemical | N1153 | Naratriptan Hydrochloride | 143388-64-1 | 250MG | $520 | 2024-03-01 | Buy |
| Cayman Chemical | 23754 | Naratriptan (hydrochloride) ≥95% | 143388-64-1 | 5mg | $34 | 2024-03-01 | Buy |
Naratriptan Hydrochloride Chemical Properties,Uses,Production
Description
Naramig was launched in Germany, Sweden and the UK for use in migraine. It is chemically available via a number of related synthetic routes all having about three steps starting from 5-bromoindole. It is a new serotonin 5-HT1B/1D receptor antagonist with modest affinity for 5-HT1a, and very weak affinity for 5-HT3 receptors. It has little or no affinity for a wide range of non-serotonin receptors including a- and padrenoceptors, dopamine, neurokinin NK1, and opiate receptors. It mediates vasoconstriction in cerebral vasculature (extra cerebral intracranial vessels), reduces neurogenic inflammation, and inhibits responses mediated by the trigeminal nerves. It has a 6- and 3-fold greater affinity for 5-HT1B, and 5-HT1D, receptors, respectively, than sumatriptan which translates to a 2-3 fold increase in potency. The reoccurance of headache was less compared to sumatriptan, zolmitriptan and rizatriptan. Naramig had no clinical effects on blood pressure or heart rate, had a long duration of action with very good tolerability, and has high oral bioavailability.
Chemical Properties
Beige Solid
Originator
Glaxo Wellcome (UK)
Uses
laxative
Uses
Naratriptan Hydrochloride is a triptan drug that is used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist
Uses
Naratriptan Hydrochloride is a triptan drug and is used for the treatment of migraine headaches
brand name
Amerge (GlaxoSmithKline).
Naratriptan Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29885 | 58 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 965 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| TopScience Biochemical | 00852-68527855 | info@itopbiochem.com | China Hong Kong | 902 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32077 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14328 | 58 |
View Lastest Price from Naratriptan Hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-13 | Naratriptan hydrochloride
143388-64-1
|
US $43.00-135.00 / mg | 99.89% | 10g | TargetMol Chemicals Inc. | ||
 |
2019-07-06 | NARATRIPTAN HYDROCHLORIDE (125 MG)F0C3600.998MG/MG(AI)
143388-64-1
|
US $2.00 / kg | 1kg | 99% | 100kg | Career Henan Chemical Co |
-
- Naratriptan hydrochloride
143388-64-1
- US $43.00-135.00 / mg
- 99.89%
- TargetMol Chemicals Inc.
-
- NARATRIPTAN HYDROCHLORIDE (125 MG)F0C3600.998MG/MG(AI)
143388-64-1
- US $2.00 / kg
- 99%
- Career Henan Chemical Co