PI 828

942289-87-4

CAS-Nr.: 942289-87-4

Englisch Name:: PI 828

Synonyma:: PI 828;PI 828,PI828;LY 294002, 4′-NH2;LY 294002, 4-NH - CAS 942289-87-4 - Calbiochem;8-(4-aminophenyl)-2-morpholin-4-ylchromen-4-one;8-(4-Aminophenyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one;2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 8-(4-aminophenyl)-2-(4-morpholinyl)-

CBNumber:: CB52455753

Summenformel:: C19H18N2O3

Molgewicht:: 322.36

MOL-Datei:: 942289-87-4.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 38

PI 828 Eigenschaften

Siedepunkt:: 534.2±50.0 °C(Predicted)

Dichte: 1.316±0.06 g/cm3(Predicted)

storage temp.: Store at +4°C

Löslichkeit: DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: slightly soluble

pka: 4.14±0.10(Predicted)

Aggregatzustand: Off-white solid

Farbe: White to yellow

Sicherheit

PI 828 Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

A cell-permeable LY 294002 (Cat. Nos. 440202 & 440204) 4′-amino derivative with enhanced potency against p110α/β/δ/γ (IC₅₀ in nM/-fold increase in potency = 183/2.7-, 98/5.7-, 1227/.5-, and 1967/1.9-, respectively). The molecule has been immobilized on epoxy-containing solid surface via the 4′-amine for binding studies and shown to interact with non-PI3K cellular proteins, such as mTOR, ALDH1, Brd4, GSK3β, and CKIIα.

Biologische Aktivität

PI 3-Kinase inhibitor (IC 50 values are 0.098, 0.183, 0.227 and 1.967 μ M for p110 β , p110 α , p110 δ and p110 γ respectively) that displays higher potency than LY 294002 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride). Can be immobilized onto a solid phase.

PI 828 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

PI 828 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 38)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4692	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9708	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9874	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 18892239720	psaitong@jm-bio.com	China	12308	58
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9730	58

942289-87-4()Verwandte Suche:

Phenylcarbamat

PI 828
2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one
8-(4-Aminophenyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one
8-(4-aminophenyl)-2-morpholin-4-ylchromen-4-one
LY 294002, 4-NH - CAS 942289-87-4 - Calbiochem
LY 294002, 4′-NH2
PI 828,PI828
4H-1-Benzopyran-4-one, 8-(4-aminophenyl)-2-(4-morpholinyl)-
942289-87-4