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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Struktur
133627-17-5
CAS-Nr.
133627-17-5
Englisch Name:
5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
Synonyma:
BIRH 414;BIRH 414 BS;Nevirapine EP Impurity A;Nevirapine Related CoMpound A;Nevirapine USP Related Compound A;11-Ethyl-4-methyl-5,11-dihydro-6H-d;Nevirapine Related Compound A (15 mg);Nevirapine EP Impurity A/ Nevirapine Related Compound A;11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one;11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
CBNumber:
CB52539709
Summenformel:
C14H14N4O
Molgewicht:
254.29
MOL-Datei:
133627-17-5.mol
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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Eigenschaften

Schmelzpunkt:
212-214℃ (1,2-dichloroethane )
Siedepunkt:
389.8±42.0 °C(Predicted)
Dichte
1.224±0.06 g/cm3(Predicted)
pka
12.05±0.20(Predicted)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
HS Code  2933997500
Bildanzeige (GHS) GHS hazard pictogramsGHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizität oral Kategorie 3 Achtung GHS hazard pictogramssrc="/GHS06.jpg" width="20" height="20" /> P264, P270, P301+P310, P321, P330,P405, P501
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H373 Kann die Organe schädigen bei längerer oder wiederholter Exposition. Spezifische Zielorgan-Toxizität (wiederholte Exposition) Kategorie 2 Warnung P260, P314, P501
Sicherheit
P260 Dampf/Aerosol/Nebel nicht einatmen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

BIRH 414 is an derivative of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine, a highly potent inhibitor of wild-type human immunodeficiency virus type 1. BIRH 414 was also shown to exhibit binding affinity towards HIV-1 reverse transcriptase enzyme. This is also an impurity found in Nevirapine (N391275).

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • Nevirapine Related CoMpound A
  • Nevirapine Related Compound A (15 mg) (5,11-dihydro-6H-11-ethyl-4-methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one)
  • BIRH 414
  • 11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • BIRH 414 BS
  • Nevirapine impurity Ⅱ{11-ethyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2′,3′-e][1,4] diazepin-6-one}
  • 11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one
  • Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • Nevirapine EP Impurity A/ Nevirapine Related Compound A
  • Nevirapine Related Compound A (15 mg)
  • 6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-ethyl-5,11-dihydro-4-methyl-
  • 11-Ethyl-4-methyl-5,11-dihydro-6H-d
  • Nevirapine EP Impurity A
  • 11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
  • Nevirapine impurity Ⅱ {11-ethyl-4-methyl-5,11-dihydr o-6H-dipyrido[3,2-b:2′,3′ -e][1,4] diazepin-6-one}
  • Nevirapine USP Related Compound A
  • Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
  • 133627-17-5
  • 25429
  • Pharmaceuticals, Intermediates & Fine Chemicals
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