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ChemicalBook >> CAS DataBase List >>5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Structure
5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one structure
CAS No.
133627-17-5
Chemical Name:
5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
Synonyms
BIRH 414;BIRH 414 BS;Nevirapine EP Impurity A;Nevirapine Related CoMpound A;Nevirapine USP Related Compound A;11-Ethyl-4-methyl-5,11-dihydro-6H-d;Nevirapine Related Compound A (15 mg);Nevirapine EP Impurity A/ Nevirapine Related Compound A;11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one;11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
CBNumber:
CB52539709
Molecular Formula:
C14H14N4O
Molecular Weight:
254.29
MDL Number:
MFCD27967300
MOL File:
133627-17-5.mol
MSDS File:
SDS
Last updated:2022-12-21 16:56:50
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5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Properties

Melting point 212-214℃ (1,2-dichloroethane )
Boiling point 389.8±42.0 °C(Predicted)
Density 1.224±0.06 g/cm3(Predicted)
pka 12.05±0.20(Predicted)
FDA UNII O3PEN5V8WL

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H317-H373
Precautionary statements  P260-P280-P301+P330+P331+P310
HS Code  2933997500

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1460725 Nevirapine Related Compound A United States Pharmacopeia (USP) Reference Standard 133627-17-5 15MG $1300 2024-03-01 Buy
TRC B399700 BIRH414 133627-17-5 100mg $1510 2021-12-16 Buy
Usbiological 162856 BIRH 414 133627-17-5 10mg $502 2021-12-16 Buy
AvaChem 3831 Nevirapine Impurity A 133627-17-5 25mg $575 2021-12-16 Buy
AvaChem 3831 Nevirapine Impurity A 133627-17-5 5mg $175 2021-12-16 Buy
Product number Packaging Price Buy
1460725 15MG $1300 Buy
B399700 100mg $1510 Buy
162856 10mg $502 Buy
3831 25mg $575 Buy
3831 5mg $175 Buy

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Chemical Properties,Uses,Production

Uses

BIRH 414 is an derivative of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine, a highly potent inhibitor of wild-type human immunodeficiency virus type 1. BIRH 414 was also shown to exhibit binding affinity towards HIV-1 reverse transcriptase enzyme. This is also an impurity found in Nevirapine (N391275).

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Preparation Products And Raw materials

Raw materials

Preparation Products

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Suppliers

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sgtlifesciences pvt ltd 		58
J & K SCIENTIFIC LTD. 76
Sinopharm Chemical Reagent Co,Ltd. 79
BOC Sciences 65
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Beijing Solarbio Science & Tecnology Co., Ltd. 68
Shanghai CR Corporation Limited 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
Chengdu MassCale Pharmaceutical Co., Ltd. 58
Shaanxi Dideu Medichem Co. Ltd 58
Nevirapine Related CoMpound A Nevirapine Related Compound A (15 mg) (5,11-dihydro-6H-11-ethyl-4-methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one) BIRH 414 11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one BIRH 414 BS Nevirapine impurity Ⅱ{11-ethyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2′,3′-e][1,4] diazepin-6-one} 11-Ethyl-5H-dipyrido[3,2-b:2'',3''-e][1,4]diazepin-6(11H)-one Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Nevirapine EP Impurity A/ Nevirapine Related Compound A Nevirapine Related Compound A (15 mg) 6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-ethyl-5,11-dihydro-4-methyl- 11-Ethyl-4-methyl-5,11-dihydro-6H-d Nevirapine EP Impurity A 11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one Nevirapine impurity Ⅱ {11-ethyl-4-methyl-5,11-dihydr o-6H-dipyrido[3,2-b:2′,3′ -e][1,4] diazepin-6-one} Nevirapine USP Related Compound A Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one Nevirapine Impurit Ⅱ5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one 11-Ethyl-4-methyl-5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one 133627-17-5 25429 Pharmaceuticals, Intermediates & Fine Chemicals