tert-Butyl 3-oxoazetidine-1-carboxylate
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- CAS-Nr.
- 398489-26-4
- Englisch Name:
- tert-Butyl 3-oxoazetidine-1-carboxylate
- Synonyma:
- 1-BOC-3-AZETIDINONE;N-Boc-3-azetidinone;N-Boc-Azetidin-3-one;3-OXO-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;tert-Butyl 3-Ox;Baricitinib-011;1-Boc azitidone;N-boc-3-azetidine;1-Boc-3-azetidione;1-Boc-3-acetidinone
- CBNumber:
- CB5282384
- Summenformel:
- C8H13NO3
- Molgewicht:
- 171.19
- MOL-Datei:
- 398489-26-4.mol
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tert-Butyl 3-oxoazetidine-1-carboxylate Eigenschaften
- Schmelzpunkt:
- 47-51 °C
- Siedepunkt:
- 251.3±33.0 °C(Predicted)
- Dichte
- 1.174±0.06 g/cm3(Predicted)
- Flammpunkt:
- 102 °C
- storage temp.
- Inert atmosphere,2-8°C
- Löslichkeit
- Chloroform (Sparingly), Dichloromethane (Slightly)
- pka
- -1.99±0.20(Predicted)
- Aggregatzustand
- Crystalline Powder
- Farbe
- White to off-white
- Sensitive
- Moisture Sensitive/Stench
- InChI
- InChI=1S/C8H13NO3/c1-8(2,3)12-7(11)9-4-6(10)5-9/h4-5H2,1-3H3
- InChIKey
- VMKIXWAFFVLJCK-UHFFFAOYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CC(=O)C1
- CAS Datenbank
- 398489-26-4(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xi,Xn |
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| R-Sätze: |
22-37/38-41 |
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| S-Sätze: |
26-39 |
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| RIDADR |
UN 3335 |
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| WGK Germany |
3 |
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| HazardClass |
IRRITANT |
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| HS Code |
29339900 |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H318 |
Verursacht schwere Augenschäden. |
Schwere Augenschädigung |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS05.jpg" width="20" height="20" /> |
P280, P305+P351+P338, P310 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
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tert-Butyl 3-oxoazetidine-1-carboxylate Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augenschäden.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
White to light brown solid
Verwenden
1-Boc-3-azetidinone can be used for the preparation of antibacterial aminoglycoside analogs.
Verwenden
tert-Butyl 3-oxoazetidine-1-carboxylate(1-Boc-3-azetidinone) is a currently common organic intermediate. It is a key intermediate for preparing various
medicaments. It can be used for preparing Janus kinase 3(JAKS), which is
a useful target for immunosuppression and transplant rejection, and can
be used for treating inflammatory disorders, autoimmune disorders,
cancer and other diseases; also useful in the preparation of a second
class of HCV protease inhibitors useful in the treatment of HCV genotype
1 infection; can also be used for preparing novel aminoglycoside
compounds with antibacterial activity; bicyclic himbacine (himbacine)
derivatives can be prepared which are useful as antagonists of the
protease activated receptor-1 (PAR-1) and are predicted to be cannabis
(CB2) receptor inhibitors, useful for the treatment of secondary
prevention of Acute Coronary Syndrome (ACS), myocardial infarction or
thrombotic stroke or peripheral arterial disease; bicyclic
azacyclobenzylamine derivatives, such as pyridopyrimidines, can be
prepared that modulate the activity of phospho-inositol 3-kinase (P13K)
and are useful in the treatment of diseases associated with P13K,
including, for example, inflammatory disorders, immune-based disorders,
cancer, and other diseases.
tert-Butyl 3-oxoazetidine-1-carboxylate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
tert-Butyl 3-oxoazetidine-1-carboxylate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 483)Lieferanten
398489-26-4()Verwandte Suche:
- Azetidin-3-one, N-BOC protected 95%
- tert-Butyl 3-oxoazetidine-1-carboxylate, 3-Oxoazetidine, N-BOC protected
- N-(t-butoxycarbonyl)azetidin-3-one
- tert-Butyl 3-oxoazetidine-1-carboxylat
- 1-Boc-3-azetidinone 97%
- 3-ketoazetidine-1-carboxylic acid tert-butyl ester
- 3-oxo-1-azetidinecarboxylic acid tert-butyl ester
- N-boc-3-azetidine
- 1-Boc-3-azetidione
- tert-Butyl 3-oxoazetidine-1-carb
- 3-OXOAZETIDINE, N-BOC PROTECTED
- TERT-BUTYL 3-OXOAZETIDINE-1-CARBOXYLATE
- 1-TERT-BUTOXYCARBONYL-3-AZETIDINONE
- 1-N-Boc-3-azetidinone
- 3-Oxoazetidine, N-BOC protected 95%
- 1-BOC-3-AZETIDINONE,97%
- N-BOC-3-OXOAZETIDINE
- 1-Azetidinecarboxylic acid, 3-oxo-, 1,1-dimethylethyl ester
- 1-BOC-3-OXOAZETIDINE
- 1-Boc-azetidin-3-one
- 1-Boc-3-acetidinone
- 3-Oxo-1-azetidinecarboxylic Acid 1,1-DiMethylethyl Ester
- tert-Butyl 3-Ox
- t-Butyl 3-oxoazetidine-1-carboxylate
- 1-Boc-3-azetidinone ,98%
- 1-Boc-3-azeetidinone
- Azetidin-3-one, N-BOC protected
- 1-(tert-Butoxycarbonyl)-3-azetidinone >
- Baricitinib-011
- ert-Butyl3-oxoazetidine-1-carboxylate
- 3-Oxo-azetidine-1-BOC
- 1-BOC-3-AZETIDINONE
- 3-OXO-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- N-Boc-Azetidin-3-one
- N-Boc-3-azetidinone
- tert-butyl -3-oxozatidine-1-carboxylate
- 1-Boc azitidone
- 398489-26-4
- 398498-26-4
- Amines
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Ring Systems
- pharmacetical
- Heterocycles series
- Azetidine
- pharmaceutical and biochemical
