6-ForMylindolo[3,2-b]carbazole

172922-91-7

CAS-Nr.: 172922-91-7

Englisch Name:: 6-ForMylindolo[3,2-b]carbazole

Synonyma:: FICZ;6-FORMYLINDOLO A CARBAZOLE;6-FORMYLINDOLO [3,2-B] CARBAZOLE;6-Formylindolo[3,2-b]carbazole (FICZ);Indolo[3,2-b]carbazole-6-carbaldehyde;5H,11H-indolo[3,2-b]carbazole-6-carbaldehyde;5,11-dihydroindolo[3,2-b]carbazole-6-carbaldehyde;5,11-Dihydroindolo[3,2-b]carbazole-6-carboxaldehyde;inhibit,Inhibitor,Aryl Hydrocarbon Receptor,AhR,FICZ;Indolo[3,2-b]carbazole-6-carboxaldehyde, 5,11-dihydro-

CBNumber:: CB5312397

Summenformel:: C19H12N2O

Molgewicht:: 284.31

MOL-Datei:: 172922-91-7.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 84

6-ForMylindolo[3,2-b]carbazole Eigenschaften

Siedepunkt:: 630.3±35.0 °C(Predicted)

Dichte: 1.463±0.06 g/cm3(Predicted)

storage temp.: -20°C

Löslichkeit: Soluble in DMSO (up to 10 mg/ml).

pka: 15.66±0.30(Predicted)

Aggregatzustand: powder

Farbe: yellow to orange

Stabilität:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

WGK Germany	1

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H302	Gesundheitsschädlich bei Verschlucken.	Akute Toxizität oral	Kategorie 4	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P270, P301+P312, P330, P501

Sicherheit

6-ForMylindolo[3,2-b]carbazole Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

6-Formylindolo[3,2-b]carbazole is a tryptophan photoproduct, suppresses pulmonary eosinophilia and Th2-type cytokine production in a mouse model of ovalbumin-induced allergic asthma.

Biochem/physiol Actions

FICZ is a potent high affinity ligand of the aryl hydrocarbon receptor (AhR), which is a ligand-activated transcription factor that activates the expression of aromatic hydrocarbon metabolizing enzyme genes such as the CYP1A1 gene and has also been shown to have multiple additional roles in cell-cycle regulation, development and maturation of many tissues, control of inflammation, and immune response. FICZ is a photoproduct of tryptophan and is believed to be an endogenous AhR ligand. It is extremely potent, with a Kd value of 0.07 nM.

6-ForMylindolo[3,2-b]carbazole Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

6-ForMylindolo[3,2-b]carbazole Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 84)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10297	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21149	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30254	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Sichuan Biosynce Pharmatech Co., Ltd.	+8619950309693	diane@biosynce.com	China	4874	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33350	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58

6-FORMYLINDOLO [3,2-B] CARBAZOLE
Indolo[3,2-b]carbazole-6-carbaldehyde
5,11-dihydroindolo[3,2-b]carbazole-6-carbaldehyde
5H,11H-indolo[3,2-b]carbazole-6-carbaldehyde
5,11-Dihydroindolo[3,2-b]carbazole-6-carboxaldehyde
6-FORMYLINDOLO A CARBAZOLE
Indolo[3,2-b]carbazole-6-carboxaldehyde, 5,11-dihydro-
6-Formylindolo[3,2-b]carbazole (FICZ)
FICZ
inhibit,Inhibitor,Aryl Hydrocarbon Receptor,AhR,FICZ
172922-91-7
C19H10N2O