ANTI-TCF-4

ANTI-TCF-4 Struktur
CAS-Nr.
Englisch Name:
ANTI-TCF-4
Synonyma:
ANTI-TCF-4;MONOCLONAL ANTI-TCF-4 (T-CELL FACTOR-4);Anti-TCF7L2 (ab1) antibody produced in rabbit;Anti-TCF7L2 (ab2) antibody produced in rabbit;Anti-Transcription factor 7-like 2 (T-cell specific, HMG-box);Monoclonal Anti-TCF-4 (T-Cell Factor-4) antibody produced in mouse
CBNumber:
CB5325351
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-TCF-4 Eigenschaften

storage temp. 
−20°C
Aggregatzustand
buffered aqueous glycerol solution

Sicherheit

WGK Germany  1

ANTI-TCF-4 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

May be used for gel-shift assays

Allgemeine Beschreibung

Transcription factor 4 or T-Cell Factor-4 (TCF-4), also called as transcription factor 7 like 2 (TCF7L2), is mapped to human chromosome 18q21.1. The gene codes for a basic helix-loop-helix DNA binding protein, which belongs to TCF family and is implicated in transcriptional regulation. It is expressed predominantly in nervous system. TCF4 protein has a transcriptional activation domain 2 (AD2), a transcriptional activation domain (AD1) and a nuclear localization signal (NLS) in the N-terminal end and a C-terminal basic helix-loop-helix (bHLH) domain, involved in dimerization and deoxyribonucleic acid (DNA) binding.

Biochem/physiol Actions

Transcription factor 4 (TCF-4) interacts functionally with β-catenin to mediate Wnt signaling pathway and transactivates downstream target genes implicated in cancer development. TCF-4 plays a vital role in development of the nervous system and vertebrate development. Aberrations or mutation of the gene leads to Pitt-Hopkins syndrome (PTHS), a rare developmental disorder characterized by severe motor and mental retardation, typical facial features and breathing abnormalities.

ANTI-TCF-4 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-TCF-4 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 4)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Riedel-de Haen AG --
United States 6773 87
SIGMA-RBI --
Switzerland 6896 91
Kamiya Biomedical Company --
ordering@kamiyabiomedical.com United States 736 72
Upstate --
info@upstate.com United States 876 76

  • ANTI-TCF-4
  • MONOCLONAL ANTI-TCF-4 (T-CELL FACTOR-4)
  • Monoclonal Anti-TCF-4 (T-Cell Factor-4) antibody produced in mouse
  • Anti-TCF7L2 (ab1) antibody produced in rabbit
  • Anti-Transcription factor 7-like 2 (T-cell specific, HMG-box)
  • Anti-TCF7L2 (ab2) antibody produced in rabbit
  • 6
  • Alphabetical Index
  • Antibodies for Gene Regulation and Expression
  • Antibodies for Immune Cell Signaling and Blood
  • Antibodies to Gene Expression/RegulationCell Biology
  • Antibodies to Transcription FactorsAntibodies
  • Antibodies to Transcription FactorsCell Biology
  • Clone Index
  • Hematopoietic Stem Cell Biology
  • Hematopoietic Stem Cell Characterization/Differentiation
  • TAntibodies
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