ANTI-PHOSPHO-TYROSINE HYDROXYLASE (PSER40)

CAS-Nr.

Englisch Name:: ANTI-PHOSPHO-TYROSINE HYDROXYLASE (PSER40)

Synonyma:: ANTI-PHOSPHO-TYROSINE HYDROXYLASE (PSER40);ANTI-RAT TYROSINE HYDROXYLASE, PHOSPHOSER 40;ANTI-TYROSINE HYDROXYLASE (PSER40) RABBIT PAB;ANTI-TYROSINE HYDROXYLASE, RAT, PHOSPHO-SPECIFIC (SER40), RAT;Anti-phospho-Tyrosine Hydroxylase (pSer40) antibody produced in rabbit

CBNumber:: CB5690172

Summenformel:

Molgewicht:: 0

MOL-Datei:: Mol file

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 4

ANTI-PHOSPHO-TYROSINE HYDROXYLASE (PSER40) Eigenschaften

storage temp.: −20°C

Aggregatzustand: aqueous glycerol solution

Sicherheit

Risiko- und Sicherheitserklärung
Gefahreninformationscode (GHS)

WGK Germany	1

Bildanzeige (GHS)

Alarmwort

Warnung

Gefahrenhinweise

Code	Gefahrenhinweise	Gefahrenklasse	Abteilung	Alarmwort	Symbol	P-Code
H315	Verursacht Hautreizungen.	Hautreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P302+P352, P321,P332+P313, P362
H319	Verursacht schwere Augenreizung.	Schwere Augenreizung	Kategorie 2	Warnung	src="/GHS07.jpg" width="20" height="20" />	P264, P280, P305+P351+P338,P337+P313P

Sicherheit

P305+P351+P338

BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

ANTI-PHOSPHO-TYROSINE HYDROXYLASE (PSER40) Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

Tyrosine Hydroxylase (TH) is encoded by the gene mapped to human chromosome 11p15.5, close to the insulin (INS) and Harvey-ras-1 (HRAS) genes. The N-terminal end of the protein plays a vital role in maintaining intracellular stability of the enzyme. tyrosine hydroxylase is expressed in various tissues such as brain, adrenal medulla and sympathetically innervated tissues. The enzyme is characterized with a regulatory domain (R), a catalytic domain (C) at N-terminal end, and a coiled-coil domain at the C-terminal end.

Biochem/physiol Actions

Tyrosine Hydroxylase (TH) specifically catalyzes the hydroxylation of the amino acid L-tyrosine to 3, 4-dihydroxy-L-phenylalanine (L-DOPA). TH is a rate-limiting enzyme involved in the synthesis of catecholamine, involved in several brain functions, such as attention, memory, cognition, and emotion. Phosphorylation of the N-terminal portion of tyrosine hydroxylase controls the degradation of this enzyme by the ubiquitin-proteasome pathway. Alteration in the expression of the gene results in the pathogenesis of Parkinson′s disease (PD). Point mutation in the gene coding for TH leads to Segawa′s syndrome.

ANTI-PHOSPHO-TYROSINE HYDROXYLASE (PSER40) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-PHOSPHO-TYROSINE HYDROXYLASE (PSER40) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 4)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Riedel-de Haen AG	--		United States	6825	87
EMD Biosciences, Inc.	--	technical@calbiochem.com	United States	6529	66
SIGMA-RBI	--		Switzerland	6913	91
Chemicon Internatinal, Inc.	--	custserv@chemicon.com	United States	4175	65

ANTI-TYROSINE HYDROXYLASE (PSER40) RABBIT PAB
ANTI-PHOSPHO-TYROSINE HYDROXYLASE (PSER40)
ANTI-RAT TYROSINE HYDROXYLASE, PHOSPHOSER 40
Anti-phospho-Tyrosine Hydroxylase (pSer40) antibody produced in rabbit
ANTI-TYROSINE HYDROXYLASE, RAT, PHOSPHO-SPECIFIC (SER40), RAT