5-hydroxy-l-tryptophan
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- CAS-Nr.
- 314062-44-7
- Englisch Name:
- 5-hydroxy-l-tryptophan
- Synonyma:
- 5-HYDROXY-L-TRYPTOPHAN;5-HTP;L-5-HTP;L-HTP-OH;5-htp 11;H-TRP(5-OH)-OH;5-HYDROXY-TRP-OH;H-5-HYDROXY-TRP-OH;5-HYDROXY-L-TRP-OH;C5-HYDROXY-L-TRYPTOPHAN
- CBNumber:
- CB6110024
- Summenformel:
- C11H12N2O3
- Molgewicht:
- 220.22
- MOL-Datei:
- 314062-44-7.mol
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5-hydroxy-l-tryptophan Eigenschaften
- Schmelzpunkt:
- 270 °C (dec.)(lit.)
- Dichte
- 0.902 g/mL at 25 °C(lit.)
- Brechungsindex
- n20/D 1.4850(lit.)
- Flammpunkt:
- 175 °F
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- Löslichkeit
- H2O: 10 mg/mL
- Aggregatzustand
- solid
- Farbe
- white
- InChI
- InChI=1/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)/t9-/s3
- InChIKey
- LDCYZAJDBXYCGN-DJEYLCQNNA-N
- SMILES
- C12C=C(C=CC=1NC=C2C[C@H](N)C(=O)O)O |&1:10,r|
- CAS Datenbank
- 314062-44-7(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
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| R-Sätze: |
22 |
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| S-Sätze: |
36 |
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| RIDADR |
UN 2811 6.1/PG 3 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
YN7110000 |
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| F |
3-10 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizität oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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5-hydroxy-l-tryptophan Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
5-hydroxy-l-tryptophan (5-HTP) is a chemical byproduct of the protein building block L-tryptophan. It is produced commercially from the seeds of an African plant known as Griffonia simplicifolia. In vivo, it is produced from tryptophan by tryptophan hydroxylase (TPH), and its decarboxylation yields serotonin (5-hydroxytryptamine, 5-HT), a monoamine neurotransmitter involved in the modulation of mood, cognition, reward, learning, memory, sleep, and numerous other physiological processes. 5-HTP is both a drug and a natural component of some dietary supplements, and occurrence in both synthetic tryptophan and 5-HTP of toxic impurities has caused eosinophilia myalgia syndrome cases[1].
History
5-hydroxy-l-tryptophan (5-HTP) has been used clinically for more than 30 yr. Sales and awareness of 5-HTP increased in 1989 after the Food and Drug Administration (FDA) banned its precursor, L-tryptophan, because of its association with eosinophilia-myalgia syndrome. Since then, 5-HTP has been marketed as a safe alternative to L-tryptophan.
5-hydroxy-l-tryptophan Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-hydroxy-l-tryptophan Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 97)Lieferanten
314062-44-7()Verwandte Suche:
- (S)-2-AMino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid hydrate
- 5-HYDROXY-TRP-OH
- 5-HYDROXY-L-TRP-OH
- 5-HTP
- (S)-2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)-PROPIONIC ACID
- C5-HYDROXY-L-TRYPTOPHAN
- H-TRP(5-OH)-OH
- H-5-HYDROXY-TRP-OH
- L-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID
- L-5-HTP
- L-5-HYDROXYTRYPTOPHAN HYDRATE
- 2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPIONIC ACID
- L-HTP-OH
- -2-Amino-3-(5-hydroxy-1H-indol-3-yl)
- Griffonia Seed Extract(5-HTP)
- (2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoicacid,hydrate
- 5-HYDROXY-L-TRYPTOPHAN USP/EP/BP
- L-5HTP(5-HYDROXY-L-TRYPTOPHAN)
- 5-HYDROXY-L-TRYPTOPHAN
- 5-htp 11
- 314062-44-7
- Unnatural Amino Acid Derivatives
- Specialty Synthesis
- Peptide Synthesis
- Tryptophans
- Indoles
- Tryptophan Derivatives
