Oxametacin

27035-30-9

CAS-Nr.: 27035-30-9

Bezeichnung:: Oxametacin

Englisch Name:: oxametacin

Synonyma:: Flogar;ABC-8/3;oxametacin;Oxametacine;oxamethacin;Indoxamic acid;1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetohydroxamic acid;1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetohydroxamic acid;1H-Indole-3-acetamide, 1-(4-chlorobenzoyl)-N-hydroxy-5-methoxy-2-methyl-;2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]-N-hydroxy-acetamide

CBNumber:: CB6939025

Summenformel:: C19H17ClN2O4

Molgewicht:: 372.806

MOL-Datei:: 27035-30-9.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 8

Oxametacin Eigenschaften

Schmelzpunkt:: 181-182° (dec)

Dichte: 1.2671 (rough estimate)

Brechungsindex: 1.6800 (estimate)

Löslichkeit: DMSO (Slightly), Methanol (Heated, Slightly)

Aggregatzustand: Solid

pka: 9.00±0.20(Predicted)

Farbe: Crystals from dioxane

Sicherheit

Toxizität	LD50 orally in rats: 96 mg/kg (De Martiis, U.S. patent)

Oxametacin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Oxametacine is prepared by the acylation of hydroxylamine with indomethacin acid chloride. Oxametacine at a dose of 100 mg is reported to be as effective as 50 mg of indomethacin in reducing pain and inflammation with a lower incidence of adverse effects.

Definition

ChEBI: A hydroxamic acid obtained by formal condensation of the carboxy group of indometacin with the amino group of hydroxylamine.

Sicherheitsprofil

Poison by ingestion and intraperitoneal routes. An anti-inflammatory agent. When heated to decomposition it emits toxic fumes of Clí and NOx.

Oxametacin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Thionyldichlorid Hydroxylammoniumchlorid Indometacin

Downstream Produkte

Oxametacin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 8)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	23962	58

27035-30-9(Oxametacin)Verwandte Suche:

Acetohydroxamsure 2-(5-Methoxyindol-3-yl)ethylamin Oxametacin

2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]-N-hydroxy-acetamide
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetohydroxamic acid
1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetohydroxamic acid
ABC-8/3
Flogar
Indoxamic acid
oxametacin
oxamethacin
Oxametacine
1H-Indole-3-acetamide, 1-(4-chlorobenzoyl)-N-hydroxy-5-methoxy-2-methyl-
27035-30-9