ZLc002

308277-46-5

CAS-Nr.: 308277-46-5

Englisch Name:: ZLc002

Synonyma:: ZLc002;EX-A5758;(S)-ZLc002;EX A5758,EXA5758;Methyl (3-methoxy-3-oxopropanoyl)-L-valinate;L-Valine, N-(3-methoxy-1,3-dioxopropyl)-, methyl ester

CBNumber:: CB69933477

Summenformel:: C10H17NO5

Molgewicht:: 231.25

MOL-Datei:: 308277-46-5.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 17

ZLc002 Eigenschaften

Siedepunkt:: 350.1±22.0 °C(Predicted)

Dichte: 1.115±0.06 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMSO: 46 mg/mL (198.92 mM);Ethanol: 46 mg/mL (198.92 mM)

pka: 12.22±0.46(Predicted)

Aggregatzustand: Solid

Farbe: Off-white to light yellow

Wasserlöslichkeit: Water: 46 mg/mL (198.92 mM)

InChI: InChI=1S/C10H17NO5/c1-6(2)9(10(14)16-4)11-7(12)5-8(13)15-3/h6,9H,5H2,1-4H3,(H,11,12)/t9-/m0/s1

InChIKey: BWPKYDAJBOUZDX-VIFPVBQESA-N

SMILES: C(OC)(=O)[C@H](C(C)C)NC(=O)CC(OC)=O

Sicherheit

ZLc002 Chemische Eigenschaften,Einsatz,Produktion Methoden

Biologische Funktion

ZLc002, a putative small-molecule inhibitor of nNOS interaction with NOS1AP, suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability. It could disrupt binding between nNOS and NOS1AP using ex-vivo, in vitro, and purified recombinant systems. In vitro, ZLc002 reduced coimmunoprecipitation of full-length NOS1AP and nNOS in cultured neurons and HEK293T cells co-expressing full-length nNOS and NOS1AP[1].

ZLc002 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ZLc002 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 17)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	5225	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Shanghai Han-Xiang Chemical Co., Ltd.	15971444841	amber@biochempartner.com	China	3063	58
Shandong Jirun Biomedical Technology Co., Ltd.	0539-0539-8613587 17661611089	2639273505@qq.com	China	165	58
ShangHai ChuanQian Chemcial Technique Centre	15869524721	3525679403@qq.com	China	3852	58
Nantong Hi-Future Biotechnology Co., Ltd	18051384581	sales@chemhifuture.com	China	3057	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	62163	58

L-Valine, N-(3-methoxy-1,3-dioxopropyl)-, methyl ester
EX-A5758
EX A5758,EXA5758
ZLc002
(S)-ZLc002
Methyl (3-methoxy-3-oxopropanoyl)-L-valinate
308277-46-5