Midostaurin

Midostaurin Struktur
120685-11-2
CAS-Nr.
120685-11-2
Englisch Name:
Midostaurin
Synonyma:
QTH113;CS-730;PKC412A;PKC 412A;PKC-412A;CGP 41231;Cgp 41251;Cgp-41251;Cgp 41 251;midostaruin
CBNumber:
CB71315281
Summenformel:
C35H30N4O4
Molgewicht:
570.64
MOL-Datei:
120685-11-2.mol

Midostaurin Eigenschaften

Schmelzpunkt:
235-260℃
Dichte
1.47±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
Löslichkeit
Soluble in DMSO (15 mg/ml), MDC (10 mg/ml), methanol (5 mg/ml), 100% ethanol (2.5 mg/ml), and DMF (20 mg/ml).
pka
14.19±0.70(Predicted)
Aggregatzustand
Tan solid
Farbe
White
Stabilität:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Sicherheit

Kennzeichnung gefährlicher T
R-Sätze: 36/37/38
HS Code  29329990

Midostaurin Chemische Eigenschaften,Einsatz,Produktion Methoden

Definition

ChEBI: An organic heterooctacyclic compound that is the N-benzoyl derivative of staurosporine.

Trademarks

Rydapt

Biologische Aktivität

Broad spectrum protein kinase inhibitor. Inhibits conventional PKC isoforms ( α , β , γ ), PDFR β , VEGFR2, Syk, PKCη, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. Displays potent antitumor activity.

Midostaurin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Midostaurin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 229)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32951 60
shandong perfect biotechnology co.ltd
+86-53169958659; +8618596095638
sales@sdperfect.com China 294 58
Hangzhou ICH Biofarm Co., Ltd
+86-0571-28186870; +undefined8613073685410
sales@ichemie.com China 998 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907
qinhe02@xaltbio.com China 997 58
Hangzhou FandaChem Co.,Ltd.
+8615858145714
FandaChem@Gmail.com China 9215 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29885 58
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 965 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
TopScience Biochemical
00852-68527855
info@itopbiochem.com China Hong Kong 902 58

120685-11-2()Verwandte Suche:


  • CGP 41251MIDOSTAURIN(PKC412)
  • N-((5S,6R,7R,9R)-6-Methoxy-14-oxo-5,6,7,8,9,14,15,16-octahydro-17-oxa-4b,9a,15-triaza-5,9-Methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-MethylbenzaMide
  • PKC-412, CGP-41251
  • Midostaurin (PKC412)
  • PKC412 (Midostaurin)
  • CGP 41231
  • N-Benzoylstaurosporine
  • (Midostaurin) Benzoylstaurosporine
  • midostaruin
  • 4'-N-benzoylstaurosporine
  • Midostaurin, Benzoylstaurosporine, 4'-N-Benzoylstaurosporine, CGP 41251
  • Benzamide, N-((9S,10R,11R,13R)-2,3,9,10,11,12-hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-J)(1,7)benzodiazonin-11-yl)-N-methyl-
  • Benzamide, N-(2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-1-oxo-8,12-epoxy-1H,8H-2,7B,12A-triazadibenzo(A,G)cyclonona(cde)trinden-10-yl)-N-methyl-, (8alpha,9beta,10beta,12alpha)-
  • Benzoylstaurosporine
  • Cgp 41 251
  • Cgp 41251
  • Cgp-41251
  • Midostaurin
  • Midostaurin [inn]
  • [9S-(9α,10β,11β,13α)]-N-(2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl)-N-methylbenzamide
  • PKC412 CGP 41231 CGP 41251 Midostaurin Benzoylstaurosporine
  • Benzamide, N-[(9S,10R,11R,13R)-2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-11-yl]-N-methyl-
  • Midostaurin USP/EP/BP
  • Midaustorin
  • N-((5S,6R,7R,9S)-6-Methoxy-5-methyl-14-oxo-5,6,7,8,9,14,15,16-octahydro-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-methylbenzamide
  • PKC412(Midostaurin,CGP41231,CGP41251)
  • PKC412 from Staurosporine
  • QTH113
  • Staurosporine, N-Benzoyl
  • MIDOSTAURIN; CGP-41251; PKC-412; PKC412;PKC 412
  • CS-730
  • MIDOSTAURIN (PKC412; CGP 41251)
  • Midoridoline
  • N-((5S,6R,7R,9R)-6-Methoxy-5-methyl-14-oxo-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-methylbenzamide
  • Midostaurin (Amorphous and Form II)
  • N-((5S,6R,7R,9R)-6-methoxy-5-methyl-14-oxo-5,6,7,8,9,14,15,16-octahydro-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-methylbenzamide
  • PKC 412A
  • PKC412A
  • PKC-412A
  • Midostaurin Impurity
  • 120685-11-2
  • 20685-11-2
  • C35H30N4O4
  • C325H30N4O4
  • antibiotic
  • Pharmaceutical
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