Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
|
|
|
- CAS-Nr.
- 118159-48-1
- Englisch Name:
- Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
- Synonyma:
- SY801;CS-1347;Bicyclol;Bicyclol, SY 801;Bicyclol USP/EP/BP;Bifendate Impurity 17;Bifendate Impurity 6 (Bicyclol);Bicyclol,SY 801,SY-801,Inhibitor,Hepatitis B virus,Autophagy,inhibit,HBV;Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate;Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
- CBNumber:
- CB72693359
- Summenformel:
- C19H18O9
- Molgewicht:
- 390.34
- MOL-Datei:
- 118159-48-1.mol
|
Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate Eigenschaften
- Siedepunkt:
- 608.1±55.0 °C(Predicted)
- Dichte
- 1.410±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- Löslichkeit
- DMSO: >10mg/mL
- pka
- 13.85±0.10(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to off-white
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
N |
|
|
| R-Sätze: |
50/53 |
|
|
| S-Sätze: |
60-61 |
|
|
| RIDADR |
UN 3077 9 / PGIII |
|
|
| RTECS-Nr. |
DT4312000 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H400 |
Sehr giftig für Wasserorganismen. |
Kurzfristig (akut) gewässergefährdend |
Kategorie 1 |
Warnung |
![GHS hazard pictograms]() src="/GHS09.jpg" width="20" height="20" /> |
P273, P391, P501 |
|
| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
|
Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Bicyclol is a hepatoprotective agent. It has antiviral activity against hepatitis B (HBV), reducing viral DNA and the secretion of the HBV antigens HBsAg and HBeAg by 59 and 35%, respectively, in infected 2.2.15 HepG2 cells.
In vivo, bicyclol reduces duck HBV (DHBV) DNA in DHBV-infected ducks at doses ≥0.4 g/kg. It also reduces the expression of TNF-α and the accumulation of lymphocytes in the liver in a mouse model of liver injury induced by concanavalin A . Oral administration of bicyclol prior to injection of diethylnitrosamine (DEN) and phenobarbital (PB; Item Nos.
9001494 |
20987) prevents formation of DEN/PB-induced hepatocellular carcinomas. It also reduces liver fibrosis in a rat model of bile duct ligation-induced hepatic fibrosis.
Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 69)Lieferanten
118159-48-1()Verwandte Suche:
- Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
- Bicyclol
- 4, 4′-dimethoxy-2, 3, 2′, 3′-bis(methylenedioxy)-6-hydroxymethyl-6′-methoxy-carbonyl biphenyl
- Bicyclol, SY 801
- CS-1347
- methyl 4-[5-(hydroxymethyl)-7-methoxy-1,3-benzodioxol-4-yl]-7-methoxy-1,3-benzodioxole-5-carboxylate
- SY801
- [4,4'-Bi-1,3-benzodioxole]-5-carboxylic acid, 5'-(hydroxymethyl)-7,7'-dimethoxy-, methyl ester
- Bicyclol USP/EP/BP
- Bicyclol,SY 801,SY-801,Inhibitor,Hepatitis B virus,Autophagy,inhibit,HBV
- Bifendate Impurity 17
- Bifendate Impurity 6 (Bicyclol)
- Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate
- 118159-48-1
- C19H18O9
