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Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate

Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate 구조식 이미지

카스 번호:: 118159-48-1

상품명:: Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate

동의어(영문):: SY801;CS-1347;Bicyclol;Bicyclol, SY 801;Bicyclol USP/EP/BP;Bifendate Impurity 17;Bifendate Impurity 6 (Bicyclol);Bicyclol,SY 801,SY-801,Inhibitor,Hepatitis B virus,Autophagy,inhibit,HBV;Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate;Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate

CBNumber:: CB72693359

분자식:: C19H18O9

포뮬러 무게:: 390.34

MOL 파일:: 118159-48-1.mol

속성

안전

용도

공급 업체 69

Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate 속성

끓는 점: 608.1±55.0 °C(Predicted)

밀도: 1.410±0.06 g/cm3(Predicted)

저장 조건: Inert atmosphere,2-8°C

용해도: DMSO: >10mg/mL

산도 계수 (pKa): 13.85±0.10(Predicted)

물리적 상태: 가루

색상: 흰색에서 황백색까지

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	N
위험 카페고리 넘버	50/53
안전지침서	60-61
유엔번호(UN No.)	UN 3077 9 / PGIII
RTECS 번호	DT4312000

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H400	수생생물에 매우 유독함	수생 환경유해성 물질 - 급성	구분 1	경고		P273, P391, P501

예방조치문구:

P273

환경으로 배출하지 마시오.

Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate C화학적 특성, 용도, 생산

개요

Bicyclol is a hepatoprotective agent. It has antiviral activity against hepatitis B (HBV), reducing viral DNA and the secretion of the HBV antigens HBsAg and HBeAg by 59 and 35%, respectively, in infected 2.2.15 HepG2 cells. In vivo, bicyclol reduces duck HBV (DHBV) DNA in DHBV-infected ducks at doses ≥0.4 g/kg. It also reduces the expression of TNF-α and the accumulation of lymphocytes in the liver in a mouse model of liver injury induced by concanavalin A . Oral administration of bicyclol prior to injection of diethylnitrosamine (DEN) and phenobarbital (PB; Item Nos. 9001494 | 20987) prevents formation of DEN/PB-induced hepatocellular carcinomas. It also reduces liver fibrosis in a rat model of bile duct ligation-induced hepatic fibrosis.

Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate 준비 용품 및 원자재

원자재

준비 용품

Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate 공급 업체

글로벌( 69)공급 업체

공급자	전화	이메일	국가	제품 수	이점
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29826	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9030	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	25859	58
Sinoway Industrial co., ltd.	0592-5800732; +8613806035118	xie@china-sinoway.com	China	990	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33350	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2985	58
Allikang Pharmaceutical Co., LTD	0573-87390950 13806705416	wzj@alicornpharma.com	China	71	58

Methyl 5'-(hydroxymethyl)-7,7'-dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5-carboxylate 관련 검색:

4-(HYDROXYMETHYL)BENZONITRILE 1,1,1-Tris(hydroxymethyl)ethane