L-NIO DIHYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
L-
NIO is a non-
selective inhibitor of all NOS isoforms. The K
i values for nNOS (rat), eNOS (bovine), and iNOS (mouse) are 1.7, 3.9, and 3.9 μM, respectively. L-
NIO inhibits endothelial-
dependent relaxation induced by acetylcholine in rat aortic rings and hypotensive responses to acetylcholine and bradykinin.
Chemische Eigenschaften
White Crystalline Solid
Verwenden
A potent and reversible inhibitor of NO synthase of adrenal glands, brain, and vascular endothelial cells
Biologische Aktivität
Potent inhibitor of endothelial NO synthase (IC 50 = 500 nM). Also inhibits iNOS and nNOS. Active in vivo .
L-NIO DIHYDROCHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
