N5-(1-イミノエチル)-L-オルニチン 化学特性,用途語,生産方法
説明
L-
NIO is a non-
selective inhibitor of all NOS isoforms. The K
i values for nNOS (rat), eNOS (bovine), and iNOS (mouse) are 1.7, 3.9, and 3.9 μM, respectively. L-
NIO inhibits endothelial-
dependent relaxation induced by acetylcholine in rat aortic rings and hypotensive responses to acetylcholine and bradykinin.
化学的特性
White Crystalline Solid
使用
A potent and reversible inhibitor of NO synthase of adrenal glands, brain, and vascular endothelial cells
生物活性
Potent inhibitor of endothelial NO synthase (IC 50 = 500 nM). Also inhibits iNOS and nNOS. Active in vivo .
N5-(1-イミノエチル)-L-オルニチン 上流と下流の製品情報
原材料
準備製品