napyradiomycin A1

103106-24-7

CAS-Nr.: 103106-24-7

Englisch Name:: napyradiomycin A1

Synonyma:: WS-9558A;Napyradiomycin A;napyradiomycin A1;3,4a-Dichloro-6,8-dihydroxy-3,4,4a,10a-tetrahydro-2,2-dimethyl-10a-(3,7-dimethyl-2,6-octadienyl)-2H-naphtho[2,3-b]pyran-5,10-dione;2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-10a-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2-dimethyl-, (3R,4aR,10aS)-

CBNumber:: CB81373343

Summenformel:: C25H30Cl2O5

Molgewicht:: 481.41

MOL-Datei:: 103106-24-7.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 10

napyradiomycin A1 Eigenschaften

Siedepunkt:: 642.5±55.0 °C(Predicted)

Dichte: 1.31±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble

Aggregatzustand: A solid

pka: 6.14±0.70(Predicted)

Sicherheit

HS Code	29419000
Toxizität	mouse,LD50,intraperitoneal,> 250mg/kg (250mg/kg),Journal of Antibiotics. Vol. 39, Pg. 487, 1986.

napyradiomycin A1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Napyradiomycin A₁ is a fungal metabolite originally isolated from C. rubra and has diverse biological activities. It is active against S. aureus, M. luteus, B. anthracis, C. bovis, and M. smegmatis (MICs = 1.56-12.5 μg/ml). Napyradiomycin A₁ is an estrogen receptor antagonist (IC₅₀ = 4.2 μM in rat uterine homogenates). It also inhibits mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinate:ubiquinone oxidoreductase (complex II) activities in bovine heart homogenates (IC₅₀s = 20 and 9.7 μM, respectively).

Verwenden

Napyradiomycin derivatives have antibacterial and tumor properties. Napyradiomycin A1 is a secondary metabolite isolated from Streptomyces. It is also an antibacterial antibiotic and an inhibitor of mitochondrial complexes I and II.

napyradiomycin A1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

napyradiomycin A1 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 10)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Zhejiang Huida Biotech Co., LTD	0571-89903882 13626641628	jiangnan@huidabiotech.com	China	3656	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
Zhejiang Huida Biotech Co., LTD	0571-0571-89903882 15990081639	sunshixuan@huidabiotech.com	China	3705	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	28118	58

103106-24-7()Verwandte Suche:

4'-Chlorvalerophenon (E)-6,10-Dimethylundeca-5,9-dien-2-on 2',4'-Dihydroxyhexanophenon 1,2,3,4-Tetrahydro-2-methylnaphthalin-1-on 4-Chlorbutyrophenon 4-Chlor-4'-hydroxybutyrophenon β-Chlorpropiophenon 1,2,3,4-Tetrahydro-5-hydroxynaphthalin-1-on 2,2'-Dichlor-diethylether 5-Chlor-1-phenylpentan-1-on

napyradiomycin A1
3,4a-Dichloro-6,8-dihydroxy-3,4,4a,10a-tetrahydro-2,2-dimethyl-10a-(3,7-dimethyl-2,6-octadienyl)-2H-naphtho[2,3-b]pyran-5,10-dione
Napyradiomycin A
WS-9558A
2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-10a-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2-dimethyl-, (3R,4aR,10aS)-
103106-24-7
C25H30Cl2O5
Antibiotic