ANTI-GFAP RAT MAB Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-Glial Fibrillary Acidic Protein antibody produced in rabbit is suitable for:
- immunohistochemical staining at a working dilution of 1:400 using rat brain sections
- immunohistochemical staining of human brain tumor tissue specimens to identify the cells expressing AQP4 (Aquaporin-4)
- immunofluorescence using brain section from mice
The antibody is suitable for immunohistochemistry at a working dilution of 1:80 using alcohol- and formalin-fixed, paraffin-embedded sections of human or animal brain tissue. It is also suitable for indirect immunoblotting at a working dilution of 1:500 using human brain extract blot and microarray.
Allgemeine Beschreibung
The GFAP (glial fibrillary acidic protein) gene encodes an intermediate protein filament-III (50kDa). It is localized particularly to the astrocytes and non-myelinating Schwann cells of the central and peripheral nervous system, respectively.
Biochem/physiol Actions
Glial Fibrillary Acidic Protein (GFAP) is expressed in several glial-related intracranial neoplasms such as astrocytomas and to a variable extent in ependymomas, medulloblastomas, choroid plexus papillomas, gangliogliomas, mixed gliomas, hemangioblastomas, pineocytomas, pineoblastomas, pituitary adenomas, retinoblastomas, oligodendrogliomas and in a small minority of peripheral nerve sheath tumors (schwannomas and neurofibromas). It may also be found in pleomorphic adenomas and ovarian and testicular teratomas.
ANTI-GFAP RAT MAB Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
