FMOC-HIS-OH
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- CAS-Nr.
- 116611-64-4
- Englisch Name:
- FMOC-HIS-OH
- Synonyma:
- Fmoc-His;FMOC-HIS-OH;Fmoc-L-His-OH;FMOC-HISTIDINE;FMOC-L-HISTIDINE;Nα-Fmoc-L-histidine;N-a-Fmoc-L-histidine;N-α-Fmoc-L-histidine;FMOC-HIS-OH USP/EP/BP;Nα-Fmoc-L-histidine99%
- CBNumber:
- CB8687841
- Summenformel:
- C21H19N3O4
- Molgewicht:
- 377.39
- MOL-Datei:
- 116611-64-4.mol
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FMOC-HIS-OH Eigenschaften
- Schmelzpunkt:
- 171-174 °C(Solv: methanol (67-56-1); water (7732-18-5))
- Siedepunkt:
- 706.7±60.0 °C(Predicted)
- Dichte
- 1.372±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- Löslichkeit
- DMSO (Slightly), DMF (Slightly, Sonicated), Methanol (Very Slightly, Heated)
- pka
- 3.26±0.10(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White
- InChIKey
- SIRPVCUJLVXZPW-IBGZPJMESA-N
- SMILES
- C(O)(=O)[C@H](CC1N=CNC=1)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitsschädlich bei Verschlucken. |
Akute Toxizität oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
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FMOC-HIS-OH Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Nα-Fmoc-L-histidine (FMOC-HIS-OH) holds great significance as a synthetic amino acid extensively employed in peptide synthesis. Its versatility makes it a highly sought-after reagent, widely used in various synthetic processes to create peptides, proteins, and even small molecules. Moreover, it catalyzes peptide and protein synthesis, further enhancing its utility. It is pivotal in unravelling biological processes such as enzymatic catalysis, protein structure, and drug design. Notably, this remarkable amino acid aids in understanding cell signalling pathways, which bear paramount importance in comprehending the mechanisms underlying diseases. The mechanism of action for Nα-Fmoc-L-histidine revolves around its ability to form essential peptide bonds. These bonds arise through a reaction with specific reagents, like DCC, leading to the creation of peptides. Subsequently, deprotection of the peptide bond occurs with the addition of a base, such as sodium hydroxide, followed by an acid, like trifluoroacetic acid.
Verwenden
Nα-Fmoc-L-histidine is an N-Fmoc-protected form of L-Histidine (H456010). L-Histidine is an essential amino acid that plays an important role in mitochondrial glutamine transport and has potential of abolishing oxidative stress caused by brain edema.L-Histidine promotes zinc uptake in human erythrocyes and also has potential as an antioxidant therapy for acute mammary inflammation in cattle.
FMOC-HIS-OH Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
FMOC-HIS-OH Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 122)Lieferanten
116611-64-4()Verwandte Suche:
- FMOC-L-HISTIDINE
- FMOC-HIS-OH
- FMOC-HISTIDINE
- N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-HISTIDINE
- N-α-Fmoc-L-histidine
- N-a-Fmoc-L-histidine
- N-.ALPHA.-FMOC -L-HISTIDINE
- Fmoc-L-His-OH
- Nα-(9H-Fluorene-9-ylmethoxycarbonyl)-L-histidine
- (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(1H-imidazol-4-yl)propanoic acid
- Fmoc-His
- N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-L-histidine
- Nα-Fmoc-L-histidine99%
- (((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine
- (9H-Fluoren-9-yl)MethOxy]Carbonyl His-OH
- (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-imidazol-5-yl)propanoic acid
- N^a-Fmoc-L-histidine,98%
- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-imidazol-5-yl)propanoicaci
- FMOC-HIS-OH USP/EP/BP
- Nα-Fmoc-L-histidine
- FMOC-L-Histidine extrapure, 98%
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanoic acid|||(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine|||FMOC-L-Histidine
- 116611-64-4
- 3116611-64-4
