2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in
Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT; IC
50 = 0.8 μg/ml). It is selective for COMT over tyrosine hydroxylase, DOPA decarboxylase, and dopamine-β-hydroxylase at 100 μg/ml. Methylspinazarin decreases blood pressure in spontaneously hypertensive rats when administered at a dose of 50 mg/kg.
2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte