ChemicalBook >> CAS DataBase List >>2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione

2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione

CAS No.
41768-12-1
Chemical Name:
2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione
Synonyms
Methylspinazarin;Methylspinazaline;2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione
CBNumber:
CB92228977
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD01327648
MOL File:
41768-12-1.mol
Last updated:2023-05-21 10:59:17

2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione Properties

storage temp. Store at -20°C
solubility Soluble in DMSO
form A solid

2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29898 Methylspinazarin 41768-12-1 500μg $227 2024-03-01 Buy
Cayman Chemical 29898 Methylspinazarin 41768-12-1 2.5mg $842 2024-03-01 Buy
AK Scientific 1857EM Methylspinazarin 41768-12-1 2.5mg $1036 2021-12-16 Buy
Product number Packaging Price Buy
29898 500μg $227 Buy
29898 2.5mg $842 Buy
1857EM 2.5mg $1036 Buy

2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione Chemical Properties,Uses,Production

Description

Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT; IC50 = 0.8 μg/ml). It is selective for COMT over tyrosine hydroxylase, DOPA decarboxylase, and dopamine-β-hydroxylase at 100 μg/ml. Methylspinazarin decreases blood pressure in spontaneously hypertensive rats when administered at a dose of 50 mg/kg.

2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione Preparation Products And Raw materials

Raw materials

Preparation Products

2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione Suppliers

Global( 7)Suppliers
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BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9708 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8864 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12007 58
2,3,5,8-Tetrahydroxy-6-methyl-1,4-naphthalenedione Methylspinazaline Methylspinazarin 41768-12-1