CID-49830258

1346527-98-7

CAS-Nr.: 1346527-98-7

Englisch Name:: CID-49830258

Synonyma:: ML240;CS-2775;ML240, >98%;CID-49830258;ML240 >=98% (HPLC);Cdc48,inhibit,VCP,Inhibitor,ML240,ML 240,ML-240,p97;2-(2-amino-1H-benzo[d]imidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amine;2-(2-Amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine;2-(2-Amino-1H-benzimidazole-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine;4-Quinazolinamine, 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-

CBNumber:: CB92751093

Summenformel:: C23H20N6O

Molgewicht:: 396.44

MOL-Datei:: 1346527-98-7.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 85

CID-49830258 Eigenschaften

Siedepunkt:: 696.6±65.0 °C(Predicted)

Dichte: 1.35±0.1 g/cm3(Predicted)

storage temp.: 2-8°C

Löslichkeit: DMSO: soluble5mg/mL, clear (warmed)

Aggregatzustand: powder

pka: 4.53±0.10(Predicted)

Farbe: white to yellow to light brown

Sicherheit

WGK Germany	3

CID-49830258 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

ML 240 is a p97 inhibitor in cancer and neurodegenerative diseases.

Biochem/physiol Actions

ML240 is a selective, ATP-competetive inhibitor of AAA ATPase p97, also called valosine containing protein (VCP). The IC50 for p97 inhibition is 110 nM. ML240 rapidly induces activity of Caspases 3 and 7, leading to apoptosis. ML240 has potent antiproliferative activity towards NCI-60 cancer cell lines.

CID-49830258 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CID-49830258 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 85)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4692	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58

2-(2-Amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine
CID-49830258
ML240
2-(2-amino-1H-benzo[d]imidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amine
2-(2-Amino-1H-benzimidazole-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine
CS-2775
ML240, >98%
4-Quinazolinamine, 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-
ML240 >=98% (HPLC)
Cdc48,inhibit,VCP,Inhibitor,ML240,ML 240,ML-240,p97
1346527-98-7
API