DBCO-maleimide
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- CAS-Nr.
- 1395786-30-7
- Englisch Name:
- DBCO-maleimide
- Synonyma:
- Dibenzocyclooctyne-maleimide;DBCO-MAL;DBCO-maleimide;DBCO-Maleimide,Dibenzocyclooctyne-maleimide;DBCO-maleimide (This product is unavailable in the U.S.);DBCO-maleimide (This product is unavailable in the U.S.) (2mg*5);Dibenzocyclooctyne-maleimide (This product is unavailable in the U.S.);1H-Pyrrole-1-propanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-2,5-dihydro-2,5-dioxo-;N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide;N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-(2,5-dioxopyrrol-1-yl)propanamide
- CBNumber:
- CB92985649
- Summenformel:
- C25H21N3O4
- Molgewicht:
- 427.45
- MOL-Datei:
- 1395786-30-7.mol
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DBCO-maleimide Eigenschaften
- Schmelzpunkt:
- 162 °C
- Siedepunkt:
- 790.5±60.0 °C(Predicted)
- Dichte
- 1.38±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- Löslichkeit
- Soluble in DMSO, DCM, DMF
- pka
- 15.03±0.46(Predicted)
- Aggregatzustand
- Solid
- Farbe
- Off-white to Gray
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher |
N |
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R-Sätze: |
50 |
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S-Sätze: |
61 |
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Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H400 |
Sehr giftig für Wasserorganismen. |
Kurzfristig (akut) gewässergefährdend |
Kategorie 1 |
Warnung |
src="/GHS09.jpg" width="20" height="20" /> |
P273, P391, P501 |
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Sicherheit |
P273 |
Freisetzung in die Umwelt vermeiden. |
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DBCO-maleimide Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.
Applications Include:
- Protein-peptide conjugates
- Antibody-enzyme or antibody-drug conjugates
- Protein or peptide-oligonucleotide conjugates
- Surface modification
DBCO-maleimide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
DBCO-maleimide Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 78)Lieferanten
- DBCO-maleimide
- Dibenzocyclooctyne-maleimide (This product is unavailable in the U.S.)
- 1H-Pyrrole-1-propanamide, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-2,5-dihydro-2,5-dioxo-
- DBCO-Maleimide,Dibenzocyclooctyne-maleimide
- DBCO-maleimide (This product is unavailable in the U.S.)
- DBCO-maleimide (This product is unavailable in the U.S.) (2mg*5)
- N-[3-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-3-oxopropyl]-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide
- Dibenzocyclooctyne-maleimide
- DBCO-MAL
- N-[3-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-3-oxopropyl]-3-(2,5-dioxopyrrol-1-yl)propanamide
- 1395786-30-7
- ADC LINKER