8-M-PDOT

134865-70-6

CAS-Nr.: 134865-70-6

Englisch Name:: 8-M-PDOT

Synonyma:: AH 002;8-M-PDOT;8 M PDOT,8MPDOT;8-METHOXY-2-PROPIONAMIDOTETRALIN;Propanamide, N-(1,2,3,4-tetrahydro-8-methoxy-2-naphthalenyl)-

CBNumber:: CB9487996

Summenformel:: C14H19NO2

Molgewicht:: 233.31

MOL-Datei:: 134865-70-6.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 29

8-M-PDOT Eigenschaften

Siedepunkt:: 447.8±45.0 °C(Predicted)

Dichte: 1.09±0.1 g/cm3(Predicted)

storage temp.: Store at RT

Löslichkeit: Soluble to 50 mM in ethanol and to 100 mM in DMSO

Aggregatzustand: Powder

pka: 15.87±0.20(Predicted)

Farbe: White to off-white

Sicherheit

8-M-PDOT Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

8-M-PDOT is a melatonin receptor 2 (MT₂) agonist (K_i = 1.12 nM). It is 5.2-fold selective for MT₂ over MT₁ receptors in a radioligand binding assay. Striatal microinfusion of 8-M-PDOT (10 μg/μl) increases the percentage of time spent in the open arms of the elevated plus maze, indicating anxiolytic-like activity, in a rat model of rotenone-induced Parkinson''s disease.

Biologische Aktivität

Melatonin receptor agonist, 20-fold selective for the MT 2 (vs MT 1 ) subtype. At human recombinant MT 1 and MT 2 receptors, displays pK i values of 8.23 and 8.95 respectively.

8-M-PDOT Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

8-M-PDOT Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 29)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9708	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840	psaitong@jm-bio.com	China	29778	58
Shanghai Universal Biotech Co.,Ltd	18768175414	gaojun@univ-bio.com	China	24998	58
Kaifeng Mingren Pharmaceutical Co.,LTD	0371-65741762	sales@hasunny.com	China	2380	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58

134865-70-6()Verwandte Suche:

Methoxyphenamin

8-METHOXY-2-PROPIONAMIDOTETRALIN
8-M-PDOT
AH 002
8 M PDOT,8MPDOT
Propanamide, N-(1,2,3,4-tetrahydro-8-methoxy-2-naphthalenyl)-
134865-70-6