8-M-PDOT
|
|
8-M-PDOT 속성
- 끓는 점
- 447.8±45.0 °C(Predicted)
- 밀도
- 1.09±0.1 g/cm3(Predicted)
- 저장 조건
- Store at RT
- 용해도
- Soluble to 50 mM in ethanol and to 100 mM in DMSO
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 15.87±0.20(Predicted)
- 색상
- White to off-white
안전
8-M-PDOT C화학적 특성, 용도, 생산
개요
8-M-PDOT is a melatonin receptor 2 (MT2) agonist (Ki = 1.12 nM). It is 5.2-fold selective for MT2 over MT1 receptors in a radioligand binding assay. Striatal microinfusion of 8-M-PDOT (10 μg/μl) increases the percentage of time spent in the open arms of the elevated plus maze, indicating anxiolytic-like activity, in a rat model of rotenone-induced Parkinson''s disease.생물학적 활성
Melatonin receptor agonist, 20-fold selective for the MT 2 (vs MT 1 ) subtype. At human recombinant MT 1 and MT 2 receptors, displays pK i values of 8.23 and 8.95 respectively.8-M-PDOT 준비 용품 및 원자재
원자재
준비 용품
8-M-PDOT 공급 업체
글로벌( 32)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 |
| TargetMol Chemicals Inc. | |
support@targetmol.com | United States | 38631 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52924 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 |
zijue.cai@tsbiochem.com | United States | 19884 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15839 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 |
info@emmx.com | United States | 8447 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9806 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11218 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988968278 |
sales@ubiochem.com | China | 4297 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; |
psaitong@jm-bio.com | China | 29774 | 58 |