RO-31-8220 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Ro 31-8220 Mesylate is a protein kinase C (PKC) inhibitor.
Allgemeine Beschreibung
Ro 31-8220 is a bisindolylmaleimide derivative of staurosporine. Ro 31-8220 blocks MAP kinase phosphatase-1 (MKP-1) expression, induces c-Jun expression and stimulates Jun N-terminal Kinase (JNK1). It has immunosuppressive properties.
Biochem/physiol Actions
Inhibitor of GRK-5 (G protein-coupled receptor kinase); PKC (protein kinase C); MAPKAP kinase 1β and p70 S6 kinase.
RO-31-8220 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte