ChemicalBook >> CAS DataBase List >>Diclofenac Sodium Salt
Diclofenac Sodium Salt
- CAS No.
- 15307-79-6
- Chemical Name:
- Diclofenac Sodium Salt
- Synonyms
- DICLOFENAC SODIUM SALT;VOLTAREN;Solaraze;tsudohmin;SODIUM 2-(2,6-DICHLOROANILINO)PHENYLACETATE;N-(2,6-Dichlorophenyl)-o-aminophenylacetic acid sodium salt;Naclof;Voldal;gp45840;kriplex
- CBNumber:
- CB00124459
- Molecular Formula:
- C14H10Cl2NNaO2
- Molecular Weight:
- 318.13
- MDL Number:
- MFCD00082251
- MOL File:
- 15307-79-6.mol
Last updated:2024-05-16 17:35:26
| Melting point | 288-290°C |
|---|---|
| Density | 0.781 g/cm3 |
| storage temp. | room temp |
| solubility | H2O: 50 mg/mL |
| form | White solid |
| pka | 4(at 25℃) |
| color | White to Almost white |
| Water Solubility | Soluble in water to 50mg/ml. |
| Merck | 14,3081 |
| BCS Class | 2 |
| Stability | Stable. |
| InChI | InChI=1S/C14H11Cl2NO2.Na/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;/h1-7,17H,8H2,(H,18,19);/q;+1/p-1 |
| InChIKey | KPHWPUGNDIVLNH-UHFFFAOYSA-M |
| SMILES | C1(=CC=CC=C1CC([O-])=O)NC1=C(Cl)C=CC=C1Cl.[Na+] |
| CAS DataBase Reference | 15307-79-6(CAS DataBase Reference) |
| NCI Dictionary of Cancer Terms | diclofenac sodium; Voltaren |
| FDA UNII | QTG126297Q |
| NCI Drug Dictionary | diclofenac sodium |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H361d-H372-H411 | |||||||||
| Precautionary statements | P201-P202-P260-P264-P273-P301+P310 | |||||||||
| Hazard Codes | T,Xi | |||||||||
| Risk Statements | 25-36/37/38-63 | |||||||||
| Safety Statements | 22-36/37-45-36-26-60-20 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AG6330000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29224999 | |||||||||
| Toxicity | LD50 in mice, rats (mg/kg): ~390, 150 orally (Krupp) | |||||||||
| NFPA 704 |
|
Diclofenac Sodium Salt price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 287840 | Diclofenac Sodium - CAS 15307-79-6 - Calbiochem | 15307-79-6 | 1G | $56.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1188800 | Diclofenac sodium United States Pharmacopeia (USP) Reference Standard | 15307-79-6 | 200mg | $436 | 2024-03-01 | Buy |
| TCI Chemical | D2508 | Diclofenac Sodium Salt >98.0%(HPLC)(N) | 15307-79-6 | 25g | $72 | 2024-03-01 | Buy |
| Alfa Aesar | J62609 | Diclofenac sodium salt | 15307-79-6 | 5g | $39.1 | 2024-03-01 | Buy |
| Alfa Aesar | J62609 | Diclofenac sodium salt | 15307-79-6 | 25g | $86.4 | 2024-03-01 | Buy |
Diclofenac Sodium Salt Chemical Properties,Uses,Production
Description
Diclofenac sodium salt is the sodium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity.
Pharmacology
Diclofenac sodium salt is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever.
Clinical Use
Diclofenac sodium salt, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes. It is often used in combination with misoprostol to prevent NSAID-induced gastric ulcers.
Side effects
Gastrointestinal problems (ulceration and bleeding) and adverse CNS reactions (dizziness and headache) are the most commonly encountered adverse effects.
Synthesis
Acylation of N-phenyl-2,6- dichloroaniline with chloroacetyl chloride gives the corresponding chloroacetanilide, which is fused with aluminum chloride to give 1-(2,6- dichlorophenyl)-2-indolinone. Hydrolysis of the indolinone with dilute aqueous-alcoholic sodium hydroxide affords the desired sodium salt directly.
Diclofenac Sodium Salt Preparation Products And Raw materials
Global( 932)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9335 | 58 |
| ZHEJIANG ESTCHEM CO.,LTD | 15957180504 | sales@zjestchem.com | China | 193 | 58 |
| Handan Tongyi New Material Technology Co., Ltd | +8617330042575 | ty003@handantongyi.com | China | 364 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12471 | 58 |
| Hong Kong Excellence Biotechnology Co., Ltd. | +86-86-18838029171 +8618126314766 | ada@sh-teruiop.com | China | 893 | 58 |
| Hebei Dangtong Import and export Co LTD | +8615632927689 | admin@hbdangtong.com | China | 986 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 | sales@sdperfect.com | China | 294 | 58 |
| Wuhan Han Sheng New Material Technology Co.，Ltd | +8617798174412 | admin01@hsnm.com.cn | China | 2118 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
Related articles
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- Dec 14，2023
- What is Diclofenac sodium?
- Diclofenac is a phenylacetic acid derivative belonging to the class of the non-selective non-steroidal anti-inflammatory drugs....
- Feb 11，2020
View Lastest Price from Diclofenac Sodium Salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-05-27 | Diclofenac 13C6-Sodium Salt
1261393-73-0
|
US $0.00-0.00 / mg | 1mg | 96% | 50 mg | Simson Pharma limited | |
 |
2021-07-09 | diclofenac sodium
15307-79-6
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2020-11-16 | Diclofenac sodium
15307-79-6
|
US $8.00 / Kg/Bag | 1Kg/Bag | 99% | 20 Tons | Longyan Tianhua Biological Technology Co., Ltd |
-
- Diclofenac 13C6-Sodium Salt
1261393-73-0
- US $0.00-0.00 / mg
- 96%
- Simson Pharma limited
-
- diclofenac sodium
15307-79-6
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Diclofenac sodium
15307-79-6
- US $8.00 / Kg/Bag
- 99%
- Longyan Tianhua Biological Technology Co., Ltd
15307-79-6(Diclofenac Sodium Salt)Related Search:
2[(2,6-dichlorophenyl)amino]-benzeneaceticacimonosodium
diclophenacsodium
gp45840
huma-difenac
kriplex
o-(2,6-dichloroanilino)phenyl-aceticacimonosodiumsalt
orthophen
ortofen
prophenatin
2-[(2,6-dichlorophenyl)amino]-benzeneacetic acid,sodium salt (1:1)
51.75/KG
Diclofenac for system suitability
AURORA KA-854
ECOFENAC
DICLOFENAC SODIUM
DICHRONIC
DICLOFENAC SODIUM DMF
NERIODIN
VALETAN
VOLTAROL
DICLOFENAC SODIUM BP
sodium [2-[(2,6-dichlorophenyl)amino]phenyl]acetate
Diclofanic potassium
DICLOFENAC SODIUM SALT USP BP JP EP
Benzeneacetic acid, 2-(2,6-dichlorophenyl)amino-, monosodium salt
DICLOFENACSODIUM,USP
DICLOFENAC SODIUM /SODIUM 2-((2,6-DICHLOROPHENYL)AMINO)PHENYL)ACETATE
DICLOFENAC-NA
2-([2,6-Dichlorophenyl] amino) benezeneacetic acid, monosodium salt
Benzeneacetic acid, 2[(2,6-dichlorophenyl)amino]-, monosodium
2-[(2,6-dichlorophenyl)amino]phenylacetate sodium
Diclofenac Sodium salt, Ph.Eur. 4th Ed.
sodium(o-((2,6-dichlorophenyl)amino)phenyl)acetate
sodium(o-(2,6-dichloroanilino)phenyl)acetate
sodiumdiclofenac
AKOS B020028
2-(2,6-DICHLOROANILINO)PHENYLACETIC ACID SODIUM SALT
2-[(2,6-DICHLOROPHENYL)AMINO]-BENZENEACETIC ACID MONOSODIUM SALT
2-[(2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, NA
2-[(2,6-DICHLOROPHENYL)AMINO]-BENZENEACETIC ACID SODIUM SALT
KROPLEX
BENFOFEN
OOTHECA MANTIDIS
Diclofenac SodiuM EC pellets 32%
DelphiMix
Diacron
Naclof
Naclofen
Novapirina
Orthofen
SorelMon
Voldal
Voltaren Ophtha
Diclofenac sodiuM COS
2-(2,6-Dichloroanilino)phenylacetic Acid Sodium Salt
Sodium 2-(2,6-Dichloroanilino)phenylacetate
Diclofenac SodiuM SR pellets 32%
Diclofenac SodiuM(EP/BP)
Aceclofenac EP IMpurity A