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Sodium Hydrocarbonate

CAS No.
144-55-8
Chemical Name:
Sodium Hydrocarbonate
Synonyms
NAHCO3;SODIUM HYDROGEN CARBONATE;BAKING SODA;sodium bicarbonate solution;Sodium bicarbonate, GR,≥99.8%;BICARBONATE OF SODA;Sodium hydrocarbonate;TSQN;Sodium bicarbonate, AR,≥99.8%;Natrium Bicarbonate
CBNumber:
CB00124969
Molecular Formula:
CHNaO3
Molecular Weight:
84.01
MDL Number:
MFCD00003528
MOL File:
144-55-8.mol
Last updated:2024-08-14 19:04:07

Sodium Hydrocarbonate Properties

Melting point >300 °C(lit.)
Boiling point 851°C
Density 2.16 g/mL at 25 °C (lit.)
refractive index 1.500
storage temp. 2-8°C
solubility H2O: 1 M at 20 °C, clear, colorless
form solution (7.5%)
color White
Specific Gravity 2.159
PH Range 7.8 - 8.2
PH 8.27(1 mM solution);8.22(10 mM solution);8.02(100 mM solution);
pka (1) 6.37, (2) 10.25 (carbonic (at 25℃)
Odor Odorless
Water Solubility 9 g/100 mL (20 ºC)
Decomposition 50 °C
Merck 14,8583
BRN 4153970
BCS Class 1
Stability Stable.
LogP -4.010 (est)
FDA 21 CFR 184.1736; 582.1736; 155.191; 310.545; 347.10
Substances Added to Food (formerly EAFUS) SODIUM BICARBONATE
SCOGS (Select Committee on GRAS Substances) Sodium bicarbonate
CAS DataBase Reference 144-55-8(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 8MDF5V39QO
NCI Drug Dictionary sodium bicarbonate
ATC code B05CB04,B05XA02
EPA Substance Registry System Sodium bicarbonate (144-55-8)
Cosmetics Info Sodium Bicarbonate

Pharmacokinetic data

Excreted unchanged in urine <1%
Volume of distribution Dependent on the physical state of the patient at the time.(L/kg)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H303
Precautionary statements  P264-P280i-P305+P351+P338-P337+P313
Safety Statements  24/25
WGK Germany  1
RTECS  VZ0950000
TSCA  Yes
HS Code  28363000
Toxicity LD50 orally in Rabbit: 4220 mg/kg
NFPA 704
0
2 1

Sodium Hydrocarbonate price More Price(125)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SX0320 Sodium bicarbonate Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs GR ACS 144-55-8 500g $27.9 2024-03-01 Buy
Sigma-Aldrich NIST2191A Sodium bicarbonate NIST? SRM? 2191a, pD Standard 144-55-8 30g $731 2024-03-01 Buy
Sigma-Aldrich 13433 Sodium bicarbonate puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E500, 99.0-100.5%, powder 144-55-8 1kg $99.7 2024-03-01 Buy
Sigma-Aldrich 13433 Sodium bicarbonate puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E500, 99.0-100.5%, powder 144-55-8 5kg $290 2024-03-01 Buy
Sigma-Aldrich 13433 Sodium bicarbonate puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E500, 99.0-100.5%, powder 144-55-8 4x5kg $1420 2024-03-01 Buy
Product number Packaging Price Buy
SX0320 500g $27.9 Buy
NIST2191A 30g $731 Buy
13433 1kg $99.7 Buy
13433 5kg $290 Buy
13433 4x5kg $1420 Buy

Sodium Hydrocarbonate Chemical Properties,Uses,Production

Chemical Properties

Sodium Hydrocarbonate is slowly decomposes to CO2 and Na2CO3 in aqueous solution at ambient temperature; decomposes to Na2CO3 in boiling water; aqueous solution slightly alkaline; pH of 0.1M solution at 25°C is about 8.3; insoluble in alcohol; decomposes in acids.

Physical properties

Sodium Hydrocarbonate is a white water-soluble crystalline solid.It has an alkaline taste, loses carbon dioxide at 270°C (518 °F).

Uses

Sodium Hydrocarbonate, used in the formof baking soda and baking powder, is the most common leavening agent; used in the manufacture of many sodium salts; source of CO2; ingredient of baking powder, effervescent salts and beverages; in fire extinguishers, cleaning Compounds.

Production Methods

Sodium Hydrocarbonate is manufactured either by passing carbon dioxide into a cold saturated solution of sodium carbonate, or by the ammonia–soda (Solvay) process, in which first ammonia and then carbon dioxide is passed into a sodium chloride solution to precipitate Sodium Hydrocarbonate while the more soluble ammonium chloride remains in solution.

Brand name

Neut (Abbott); Soda Mint (Lilly)

Chemical Reactivity

Sodium Hydrocarbonate can often be used as a safer alternative to sodium hydroxide, and as such can be used as a wash to remove any acidic impurities from a "crude" liquid, producing a purer sample.

Reaction of Sodium Hydrocarbonate and an acid produces a salt and carbonic acid, which readily decomposes to carbon dioxide and water: NaHCO3 + HCl → NaCl + H2O+CO2 H2CO3 → H2O + CO2(g)

Sodium Hydrocarbonate reacts with acetic acid (found in vinegar), producing sodium acetate, water, and carbon dioxide: NaHCO3 + CH3COOH → CH3COONa + H2O + CO2(g)

Pharmaceutical Applications

Sodium Hydrocarbonate is usually administered orally in order to regulate the serum pH. Imbalances of the plasma pH can be due to problems occurring in the kidneys such as renal tubular acidosis. Within the kidneys, blood is filtered before it passes through the tubular part of the nephrons where re-absorption or secretion of important salts and others takes place. In renal tubular acidosis, the kidneys either fail to filter or secrete acid ions (H+) from the plasma (secretion takes place in the distal tubule), or to recover bicarbonate ions (HCO3-) from the filtrate (passive re-absorption takes place in the proximal tubule, active re-absorption at the distal tubule), which is necessary to balance the pH. In the view of this mode of action, the pharmaceutically active component of Sodium Hydrocarbonate is the bicarbonate anion, but the cation Na+ is responsible for solubility and compatibility.

Clinical Use

Sodium Hydrocarbonate is indicated to treat metabolic acidosis and alkalinize the urine. It is also used as adjunctive therapy in treating hypercalcemic or hyperkalemia crises.

108-77-0
227626-61-1
227626-62-2
144-55-8
Synthesis of Sodium Hydrocarbonate from Cyanuric chloride and Carbamic acid, [[1-(2-amino-2-oxoethyl)cyclohexyl]methyl]-, 1,1-dimethylethyl ester (9CI)
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