Ursodeoxycholic
- CAS No.
- 128-13-2
- Chemical Name:
- Ursodeoxycholic
- Synonyms
- UDCA;URSODIOL;URSODESOXYCHOLIC ACID;Ursodeoxycholic;URSODEOXYCHOLATE;3-alpha,7-beta-dihydroxy-5-beta-cholanoicacid;Tauroursodiol;Urosodeoxycholic Acid;actigall;3-alpha,7-beta-dihydroxy-5-beta-cholan-24-oicaci
- CBNumber:
- CB00126431
- Molecular Formula:
- C24H40O4
- Molecular Weight:
- 392.57
- MDL Number:
- MFCD00003680
- MOL File:
- 128-13-2.mol
- MSDS File:
- SDS
Melting point | 203-204 °C (lit.) |
---|---|
Boiling point | 437.26°C (rough estimate) |
alpha | 60 º (c=2, EtOH) |
Density | 0.9985 (rough estimate) |
refractive index | 60.5 ° (C=2, EtOH) |
Flash point | 9℃ |
storage temp. | 2-8°C |
solubility | ethanol: 50 mg/mL, clear |
pka | pKa 5.04±0.04(H2O t = 25.0±0.1 I = 0.00)(Approximate) |
form | Solid. Powder. |
color | White - almost white. |
Water Solubility | practically insoluble |
Merck | 14,9889 |
BRN | 3219888 |
InChIKey | RUDATBOHQWOJDD-UZVSRGJWSA-N |
LogP | 3-3.38 at 20℃ |
CAS DataBase Reference | 128-13-2(CAS DataBase Reference) |
NCI Dictionary of Cancer Terms | ursodiol |
FDA UNII | 724L30Y2QR |
NCI Drug Dictionary | Actigall |
ATC code | A05AA02 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319 | |||||||||
Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 24/25-36-26 | |||||||||
RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
WGK Germany | 2 | |||||||||
RTECS | FZ2000000 | |||||||||
F | 10 | |||||||||
HS Code | 29181990 | |||||||||
Toxicity | LD50 in mice (g/kg): 0.1 i.v. (Ardenne, Reitnauer); in rats, mice (mg/kg): 2000, 6000 s.c.; 1000, 1200 i.p., 310, 260 i.v. (Ward) | |||||||||
NFPA 704 |
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Ursodeoxycholic price More Price(36)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | PHR1579 | Ursodiol Pharmaceutical Secondary Standard; Certified Reference Material | 128-13-2 | 500mg | $105 | 2024-03-01 | Buy |
Sigma-Aldrich | 1707806 | Ursodiol United States Pharmacopeia (USP) Reference Standard | 128-13-2 | 125mg | $358 | 2024-03-01 | Buy |
Sigma-Aldrich | BP706 | Ursodeoxycholic acid British Pharmacopoeia (BP) Reference Standard | 128-13-2 | 150MG | $266 | 2023-06-20 | Buy |
Alfa Aesar | B20490 | Ursodeoxycholic acid 99% | 128-13-2 | 1g | $40.7 | 2023-06-20 | Buy |
Alfa Aesar | B20490 | Ursodeoxycholic acid 99% | 128-13-2 | 5g | $117 | 2023-06-20 | Buy |
Ursodeoxycholic Chemical Properties,Uses,Production
Description
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool. It is a medication used in the management and treatment of cholestatic liver disease.
Uses
Ursodeoxycholic acid is a naturally occurring hydrophilic bile acid which has been demonstrated to decrease cholestasis. Ursodiol has been postulated to reduce the hydrophobic bile acids in the hepatobiliary system to lessen the potential for hepatotoxicity. It has been extensively evaluated in prophylaxis of SOS, with modest benefits. Ursodiol has also been postulated to exhibit immunomodulatory and antiapoptotic properties and may be used as an adjunctive therapy for patients with acute or chronic GVHD of the liver.
Ursodeoxycholic Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Pharmaceuticals Group Corp., Ltd. | +8613004379774 | wu@jiaerke.com | China | 33 | 58 |
Handan Tongyi New Material Technology Co., Ltd | +8617330042575 | ty003@handantongyi.com | China | 351 | 58 |
Xinyi Dajiang Chemical Co.,Ltd. | +8617314178111 | 243096958@qq.com | China | 5 | 58 |
XuZhou Magic Biotechnology Co., Ltd. | +undefined13921770081 | SVP01@magicbiotech.cn | China | 92 | 58 |
Wuhan Han Sheng New Material Technology Co.,Ltd | +8617798174412 | admin01@hsnm.com.cn | China | 2097 | 58 |
Hebei Fengmu Trading Co., Ltd. | +8613393234347 | Lyla@fengmuchem.com | China | 2948 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8812 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5978 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 988 | 58 |
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View Lastest Price from Ursodeoxycholic manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-07-27 | Ursodeoxycholic acid
128-13-2
|
US $100.00 / kg | 1kg | 99% | 1000tons | Henan Bao Enluo International TradeCo.,LTD | ||
2021-01-14 | Ursodeoxycholic Acid
128-13-2
|
US $1.00 / g | 10g | 99% | 10000kgs | WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD | ||
2019-07-06 | Ursodeoxycholic acid
128-13-2
|
US $1.00 / KG | 1G | 98% | 100KG | Career Henan Chemical Co |
- Ursodeoxycholic acid
128-13-2
- US $100.00 / kg
- 99%
- Henan Bao Enluo International TradeCo.,LTD
- Ursodeoxycholic Acid
128-13-2
- US $1.00 / g
- 99%
- WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
- Ursodeoxycholic acid
128-13-2
- US $1.00 / KG
- 98%
- Career Henan Chemical Co