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Ursodeoxycholic

CAS No.
128-13-2
Chemical Name:
Ursodeoxycholic
Synonyms
UDCA;URSODIOL;URSODESOXYCHOLIC ACID;Ursodeoxycholic;URSODEOXYCHOLATE;3-alpha,7-beta-dihydroxy-5-beta-cholanoicacid;Tauroursodiol;Urosodeoxycholic Acid;actigall;3-alpha,7-beta-dihydroxy-5-beta-cholan-24-oicaci
CBNumber:
CB00126431
Molecular Formula:
C24H40O4
Molecular Weight:
392.57
MDL Number:
MFCD00003680
MOL File:
128-13-2.mol
MSDS File:
SDS
Last updated:2024-11-19 15:53:33

Ursodeoxycholic Properties

Melting point 203-204 °C (lit.)
Boiling point 437.26°C (rough estimate)
alpha 60 º (c=2, EtOH)
Density 0.9985 (rough estimate)
refractive index 60.5 ° (C=2, EtOH)
Flash point 9℃
storage temp. 2-8°C
solubility ethanol: 50 mg/mL, clear
pka pKa 5.04±0.04(H2O t = 25.0±0.1 I = 0.00)(Approximate)
form Solid. Powder.
color White - almost white.
Water Solubility practically insoluble
Merck 14,9889
BRN 3219888
InChIKey RUDATBOHQWOJDD-UZVSRGJWSA-N
LogP 3-3.38 at 20℃
CAS DataBase Reference 128-13-2(CAS DataBase Reference)
NCI Dictionary of Cancer Terms ursodiol
FDA UNII 724L30Y2QR
NCI Drug Dictionary Actigall
ATC code A05AA02

Pharmacokinetic data

Protein binding 96-98%

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  2
RTECS  FZ2000000
10
HS Code  29181990
Toxicity LD50 in mice (g/kg): 0.1 i.v. (Ardenne, Reitnauer); in rats, mice (mg/kg): 2000, 6000 s.c.; 1000, 1200 i.p., 310, 260 i.v. (Ward)
NFPA 704
0
0 0

Ursodeoxycholic price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR1579 Ursodiol Pharmaceutical Secondary Standard; Certified Reference Material 128-13-2 500mg $105 2024-03-01 Buy
Sigma-Aldrich 1707806 Ursodiol United States Pharmacopeia (USP) Reference Standard 128-13-2 125mg $358 2024-03-01 Buy
Sigma-Aldrich BP706 Ursodeoxycholic acid British Pharmacopoeia (BP) Reference Standard 128-13-2 150MG $266 2023-06-20 Buy
Alfa Aesar B20490 Ursodeoxycholic acid 99% 128-13-2 1g $40.7 2023-06-20 Buy
Alfa Aesar B20490 Ursodeoxycholic acid 99% 128-13-2 5g $117 2023-06-20 Buy
Product number Packaging Price Buy
PHR1579 500mg $105 Buy
1707806 125mg $358 Buy
BP706 150MG $266 Buy
B20490 1g $40.7 Buy
B20490 5g $117 Buy

Ursodeoxycholic Chemical Properties,Uses,Production

Description

Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool. It is a medication used in the management and treatment of cholestatic liver disease.

Uses

Ursodeoxycholic acid is a naturally occurring hydrophilic bile acid which has been demonstrated to decrease cholestasis. Ursodiol has been postulated to reduce the hydrophobic bile acids in the hepatobiliary system to lessen the potential for hepatotoxicity. It has been extensively evaluated in prophylaxis of SOS, with modest benefits. Ursodiol has also been postulated to exhibit immunomodulatory and antiapoptotic properties and may be used as an adjunctive therapy for patients with acute or chronic GVHD of the liver.

10538-55-3
128-13-2
Synthesis of Ursodeoxycholic from Deoxyursocholic acid methyl ester
Global( 789)Suppliers
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View Lastest Price from Ursodeoxycholic manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ursodeoxycholic acid pictures 2023-07-27 Ursodeoxycholic acid
128-13-2
US $100.00 / kg 1kg 99% 1000tons Henan Bao Enluo International TradeCo.,LTD
Ursodeoxycholic Acid pictures 2021-01-14 Ursodeoxycholic Acid
128-13-2
US $1.00 / g 10g 99% 10000kgs WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
Ursodeoxycholic acid pictures 2019-07-06 Ursodeoxycholic acid
128-13-2
US $1.00 / KG 1G 98% 100KG Career Henan Chemical Co
Ursodeoxycholic acid(micronized) URSODEOXYCHOLIC ACID URSODEOXYCHOLOC ACID UDCS 17-beta-(1-methyl-3-carboxypropyl)etiocholane-3-alpha,7-beta-diol acidoursodeossicolico arsacol cholit-ursan delursan destolit deursil litursol lyeton peptarom solutrat ursacol ursobilin ursochol 3a,7b-Dihydroxy-5b-cholan-24-oate 3a,7b-Dihydroxy-5b-cholanic acid 3a,7b-Dihydroxy-5b-cholanoic acid 3a,7b-Dihydroxycholanic acid 5b-Cholan-24-oic acid, 3a,7b-dihydroxy- (8CI) 5b-Cholanic acid, 3a,7b-dihydroxy- (7CI) 7b-Hydroxylithocholic acid Cholan-24-oic acid, 3,7-dihydroxy-, (3a,5b,7b)- (9CI) Desocol Desol NSC 683769 Paptarom Urdes Ursolvan Urodeoxycholic acid Ursodiol, 7-Hydroxylithocholic Acid 3α,7β-Dihydroxy-5β-cholan-24-oic acid, 5β-Cholan-24-oic acid-3α,7β-diol, 7β-Hydroxylithocholic acid, UDCS Ursodeoxycholic-2,2,3,4,4-d5 acid Ursodeoxycholic acid,Ursodiol delursan 250 Ursodiol (Ursodeoxycholic Acid) Ursodeoxycholic acid,3α,7β-Dihydroxy-5β-cholan-24-oic acid, 5β-Cholan-24-oic acid-3α,7β-diol, 7β-Hydroxylithocholic acid, UDCS Ursodiol (125 mg) Ursodeoxycholic Acid, EP Ursodesoxycholic acid (UDCA) 5beta-Cholanic Acid-3alpha,7beta-diol 3alpha,7beta-Dihydroxy-5beta-cholanic Acid Ursocol Ursodeoxycholic acid,99% Adursal Ursic acid 34784-46-7 (3a,5b,7b)-3,7-Dihydroxycholan-24-oic acid 7BETA-HYDROXYLITHOCHOLIC ACID 6BETA-CHOLANIC ACID-3A,7BETA-DIOL (6-BETA)-CHOLANIC ACID-(3-ALPHA)-(7-BETA)-DIOL 3A,7B-DIHYDROXY-5B-CHOLAN-24-OIC ACID 3ALPHA, 7BETA-DIHYDROXY-5BETA-CHOLANIC ACID 3ALPHA,7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID 3alpha,7beta-dihydroxy-6beta-cholan-24-oic acid 3ALPHA, 7BETA-DIOXYCHOLANIC ACID