Isoprenaline
- CAS No.
- 7683-59-2
- Chemical Name:
- Isoprenaline
- Synonyms
- isoprenaline;A 21;isoprel;Aludrin;asmalar;Aludrine;NSC 9975;Lomupren;Aleudrine;ICI 46399
- CBNumber:
- CB00127981
- Molecular Formula:
- C11H17NO3
- Molecular Weight:
- 211.26
- MDL Number:
- MOL File:
- 7683-59-2.mol
- MSDS File:
- SDS
| Melting point | 170.5°C |
|---|---|
| Boiling point | 350.94°C (rough estimate) |
| Density | 1.1240 (rough estimate) |
| refractive index | 1.5718 (estimate) |
| pka | 8.64(at 25℃) |
| FDA UNII | L628TT009W |
| NIST Chemistry Reference | 3,4-Dihydroxy-«alpha»-(isopropylaminomethyl)-benzyl alcohol(7683-59-2) |
| ATC code | C01CA02,R03AB02,R03CB01,R03CB51 |
Isoprenaline price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0006523 | ISOPRENALINE 95.00% | 7683-59-2 | 1G | $166.95 | 2021-12-16 | Buy |
| Crysdot | CD12033527 | 4-(1-Hydroxy-2-(isopropylamino)ethyl)benzene-1,2-diol 97% | 7683-59-2 | 1g | $495 | 2021-12-16 | Buy |
| Alichem | 7683592 | 4-(1-Hydroxy-2-(isopropylamino)ethyl)benzene-1,2-diol | 7683-59-2 | 1g | $509.85 | 2021-12-16 | Buy |
| Crysdot | CD12033527 | 4-(1-Hydroxy-2-(isopropylamino)ethyl)benzene-1,2-diol 97% | 7683-59-2 | 5g | $1035 | 2021-12-16 | Buy |
| Crysdot | CD12033527 | 4-(1-Hydroxy-2-(isopropylamino)ethyl)benzene-1,2-diol 97% | 7683-59-2 | 10g | $1575 | 2021-12-16 | Buy |
Isoprenaline Chemical Properties,Uses,Production
Uses
Isoprenaline is a non-selective β-adrenergic receptor agonist.It is used to treat heart block and episodes of Adams–Stokes syndrome that are not caused by ventricular tachycardia or fibrillation. It is also used to prevent Torsades de Pointes in patients with long QT refractory to magnesium and to treat patients with intermittent Torsades de Pointes refractory to treatment with magnesium.
Brand name
Isoprenaline is marketed under many brand names worldwide, including Aleudrina, Asthpul, Iludrin, Isomenyl, Isuprel, Neo-Epinine, Neodrenal, Proternol, and Saventrine.
Mechanism of action
Isoprenaline is a β1 and β2 adrenoreceptor agonist and has almost no activity on alpha adrenergic receptors at low levels.However, at higher concentrations, isoprenaline can evoke α-AR-mediated responses. Its agonist effects at TAAR1 provide it with pharmacodynamic effects that resemble those of the endogenous trace amines, like tyramine.
Pharmacology
Isoprenaline has a positive inotropic and chronotropic effects, increasing cardiac output by increasing the heart rate and cardiac contractility. Isoprenaline also decreases diastolic blood pressure by lowering peripheral vascular resistance.
Side effects
Tachycardia, cardiac arrhythmias, palpitations, hypotension, hypertension
Tremor
Headache, dizziness
Sweating, facial flushing
Both isoprenaline salts have a low pH and may cause venous irritation and tissue damage in cases of extravasation.
Isoprenaline Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2141 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34571 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15395 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52861 | 58 |
| XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD | +8617731987558 | xingjiu@xingjiubiotech.com | China | 990 | 58 |
| Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 | mack@tongyon.com | China | 2996 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
View Lastest Price from Isoprenaline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-08-21 | Sodium tetraborate pentahydrate
12179-04-3
|
1kg | 99% | 100tons | Anhui Ruihan Technology Co., Ltd |
-
- Sodium tetraborate pentahydrate
12179-04-3
- 99%
- Anhui Ruihan Technology Co., Ltd