Cyanocobalamine
- CAS No.
- 68-19-9
- Chemical Name:
- Cyanocobalamine
- Synonyms
- CYANOCOBALAMIN;Vb12;METHYLCOBALAMIN;CYANOCOBALAMINE;hemomin;cyanocobalamin (b12);COBALAMINE;hydroxycobalamin chloride;VIT B12;lldfactor
- CBNumber:
- CB00129348
- Molecular Formula:
- C63H88CoN14O14P
- Molecular Weight:
- 1355.37
- MDL Number:
- MFCD00151092
- MOL File:
- 68-19-9.mol
- MSDS File:
- SDS
| Melting point | >300°C |
|---|---|
| alpha | 23656 -59 ± 9° (dil aq soln) |
| Boiling point | >300 °C |
| Flash point | 9℃ |
| storage temp. | 2-8°C |
| solubility | Sparingly soluble in water and in ethanol (96 per cent), practically insoluble in acetone. The anhydrous substance is very hygroscopic. |
| pka | pKa 3.28±0.04(H2O,D2O t=23±0.5 Iunspeci?ed) (Uncertain) |
| form | Crystalline Powder or Crystals |
| color | Red to dark red |
| Odor | dark red cryst. or powd., odorless and tasteless |
| Water Solubility | Soluble |
| Sensitive | Hygroscopic |
| Merck | 14,10014 |
| BRN | 4122889 |
| Exposure limits | NIOSH: IDLH 25 mg/m3 |
| Stability | Hygroscopic. Keep cold and dry. |
| InChIKey | RMRCNWBMXRMIRW-WZHZPDAFSA-L |
| LogP | 3.570 (est) |
| Substances Added to Food (formerly EAFUS) | VITAMIN B-12 |
| SCOGS (Select Committee on GRAS Substances) | Vitamin B12 (cyanocobalamin) |
| NCI Dictionary of Cancer Terms | cyanocobalamin |
| FDA UNII | P6YC3EG204 |
| NCI Drug Dictionary | Berubigen |
| ATC code | B03BA01,B03BA51 |
| EPA Substance Registry System | Vitamin B12 (68-19-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H301+H311+H331-H370 | |||||||||
| Precautionary statements | P210-P260-P280-P301+P310-P311 | |||||||||
| Hazard Codes | ||||||||||
| HS Code | 2936260000 | |||||||||
| Toxicity | LD50 intravenous in mouse: 2gm/kg | |||||||||
| NFPA 704 |
|
Cyanocobalamine price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | V-019 | Cyanocobalamin (Vitamin B12) solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 68-19-9 | 1mL | $85.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | C3607 | Cyanocobalamin meets USP testing specifications | 68-19-9 | 5g | $762 | 2024-03-01 | Buy |
| Sigma-Aldrich | 47869 | Cyanocobalamin (B12) analytical standard | 68-19-9 | 100mg | $44.9 | 2024-03-01 | Buy |
| Sigma-Aldrich | 43107 | Cyanocobalamin tested according to Ph. Eur. | 68-19-9 | 10G | $1460 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1152011 | Cyanocobalamin (crystallline) United States Pharmacopeia (USP) Reference Standard | 68-19-9 | 2X150MG | $447 | 2024-03-01 | Buy |
Cyanocobalamine Chemical Properties,Uses,Production
Description
Cyanocobalamin is a synthetic compound of vitamin B12 used to treat vitamin deficiencies. Chemically, cyanocobalamin is classified as a "corrinoid," representing a crystallizable cobalt complex. The name "cyanocobalamin" is derived from including a cyanide group within the molecule. Vitamin B12 facilitates several methylation reactions within the body. Methylcobalamin serves as a cofactor in the conversion of homocysteine to methionine in the body. Furthermore, in the form of adenosylcobalamin, the vitamin is crucial in converting methylmalonyl-coenzyme A (CoA) to succinyl-CoA. Both of these reactions are essential for cell division and growth.
Uses
Cyanocobalamin is approved by the United States Food and Drug Administration (FDA) for pernicious anemia, malabsorption, atrophic gastritis, gastrectomy, Helicobacter pylori infection, and other conditions.
Side effects
Cyanocobalamine can cause a variety of adverse drug reactions, including allergic reactions such as itching, erythema, and clammy skin. Its dermal adverse drug reactions include acne, rosacea, and allergic reactions to cyanocobalamin injections. Other common adverse reactions include: shortness of breath (even with mild exertion), swelling, rapid weight gain; pulmonary oedema, congestive heart failure, peripheral vascular thrombosis; hypokalaemia (leg cramps, arrhythmia, tingling/numbness, muscle weakness, or claudication sensation); numbness or tingling and joint pain; fever; swelling of the tongue; itchiness or rash; and erythrocytosis.
Cyanocobalamine Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| APOLLO HEALTHCARE RESOURCES | +6596580999 | sales@apollo-healthcare.com.sg | Singapore | 399 | 58 |
| Siyang Liaoning Biochemical Products Co. Ltd | +86-15221114306; +8615221114306 | 2594582574@qq.com | China | 561 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 | gksales1@gk-bio.com | China | 9315 | 58 |
| TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD | +86-576-88902229;+86-0576-88902229 +8613968687450 | yuxin@yuxchem.com | China | 167 | 58 |
| Watson Biotechnology Co.,Ltd | +86-18186686046 +86-18186686046 | sales01@watsonbiotech.cn | China | 5822 | 58 |
| Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 660 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +86-15350851019 +86-15383190639 | admin@86-ss.com | China | 1000 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3882 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12837 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5858 | 58 |
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View Lastest Price from Cyanocobalamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-08-21 | Sodium tetraborate pentahydrate
12179-04-3
|
1kg | 99% | 100tons | Anhui Ruihan Technology Co., Ltd |
-
- Sodium tetraborate pentahydrate
12179-04-3
- 99%
- Anhui Ruihan Technology Co., Ltd