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5-Bromo-4,7-diazaindole

CAS No.
875781-43-4
Chemical Name:
5-Bromo-4,7-diazaindole
Synonyms
2-Bromo-5H-pyrrolo[2,3-b]pyrazine;Upatinib Impurity 94;5-BROMO-4,7-DIAZAINDOLE;5-Bromo-4,7-diazaindole 97%;5H-Pyrrolo[2,3-b]pyrazine, 2-bromo-;4H-Pyrrolo[2,3-b]pyrazine, 2-bromo-;2-broMo-5H-pyrrolo[2,3-b]pyrazine 2-broMo-5H-pyrrolo[3,2-b]pyrazine
CBNumber:
CB01012860
Molecular Formula:
C6H4BrN3
Molecular Weight:
198.02
MDL Number:
MFCD09834822
MOL File:
875781-43-4.mol
MSDS File:
SDS
Last updated:2024-05-15 10:06:35

5-Bromo-4,7-diazaindole Properties

Boiling point 265 °C
Density 2.00
Flash point 114 °C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form yellow solid
pka 10.58±0.50(Predicted)
InChI InChI=1S/C6H4BrN3/c7-5-3-9-6-4(10-5)1-2-8-6/h1-3H,(H,8,9)
InChIKey KTKMLXBEBKGQGL-UHFFFAOYSA-N
SMILES C12NC=CC1=NC(Br)=CN=2
CAS DataBase Reference 875781-43-4

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2933998090

5-Bromo-4,7-diazaindole price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B698910 2-Bromo-5h-pyrrolo[2,3-b]pyrazine 875781-43-4 100mg $45 2021-12-16 Buy
TRC B698910 2-Bromo-5h-pyrrolo[2,3-b]pyrazine 875781-43-4 500mg $65 2021-12-16 Buy
Synthonix B0088 5-Bromo-4,7-diazaindole 97.0% 875781-43-4 1g $30 2021-12-16 Buy
Matrix Scientific 068431 5-Bromo-4,7-diazaindole >95% 875781-43-4 250mg $45 2021-12-16 Buy
Biosynth Carbosynth FB138216 2-Bromo-5H-pyrrolo[3,2-b]pyrazine 875781-43-4 250mg $60 2021-12-16 Buy
Product number Packaging Price Buy
B698910 100mg $45 Buy
B698910 500mg $65 Buy
B0088 1g $30 Buy
068431 250mg $45 Buy
FB138216 250mg $60 Buy

5-Bromo-4,7-diazaindole Chemical Properties,Uses,Production

Synthesis

Potassium tert-butoxide (3.70 g, 33.0 mmol) was dissolved in THF (80 mL) under N2 protection. A solution of 5-bromo-3 - ((trimethylsilyl) ethynyl) pyrazine-2-amino (9.00 g, 33.0 mmol) in THF (84 mL) was slowly added dropwise over 30 min. After the dropwise addition, the mixture was stirred at room temperature for 30 min, Reflux reaction 1h, Cooled to room temperature and filtered. The filter cake was washed with ethyl acetate (200 mL) and saturated brine (50 mL x 2), and the aqueous phase was combined. And extracted with ethyl acetate (60 mL x 2). The organic phases were combined. The residue was subjected to column chromatography (eluent: PE / EtOAc (v / v) = 3/1) to give 5-Bromo-4,7-diazaindole 5.0 g of a yellow solid.

875781-41-2
875781-43-4
Synthesis of 5-Bromo-4,7-diazaindole from 5-bromo-3-((trimethylsilyl)ethynyl)pyrazin-2-amine
Global( 273)Suppliers
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Henan Fengda Chemical Co., Ltd
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Capot Chemical Co.,Ltd.
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Shanghai Jinghao Pharmaceutical Co.,Ltd
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Shanghai Yingrui Biopharma Co.,Ltd
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View Lastest Price from 5-Bromo-4,7-diazaindole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Bromo-4,7-diazaindole pictures 2025-04-04 5-Bromo-4,7-diazaindole
875781-43-4
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
5-Bromo-4,7-diazaindole pictures 2024-04-11 5-Bromo-4,7-diazaindole
875781-43-4
US $5.00-0.10 / KG 1KG 98% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
5-Bromo-4,7-diazaindole pictures 2019-09-05 5-Bromo-4,7-diazaindole
875781-43-4
US $6.00 / KG 1KG 95%-98% 100 Career Henan Chemical Co

5-Bromo-4,7-diazaindole Spectrum

5-BROMO-4,7-DIAZAINDOLE 5H-Pyrrolo[2,3-b]pyrazine, 2-bromo- 2-broMo-5H-pyrrolo[2,3-b]pyrazine 2-broMo-5H-pyrrolo[3,2-b]pyrazine 4H-Pyrrolo[2,3-b]pyrazine, 2-bromo- 5-Bromo-4,7-diazaindole 97% 2-Bromo-5H-pyrrolo[2,3-b]pyrazine Upatinib Impurity 94 875781-43-4 upadacitinib